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Head-to-head evidence comparison — which supplement is right for you?
Fenugreek wins 2 of 3 categories. Both are solid choices — the best pick depends on your specific goals.
Verdict
Likely helps
12 of 13 studies with measurable effects showed benefit.
Top outcomes
Verdict
Mixed evidence
4 of 11 studies with measurable effects showed benefit.
Top outcomes
Shared outcomes (1)
Outcomes where both Fenugreek and Iodine have evidence — compare verdict strength side-by-side.
500-600mg extract (standardized)
With meals
Standardized extract (Testofen, Furosap)
150-300mcg for maintenance; higher only if deficient under supervision
Any time with food
Potassium iodide (most common and studied)
4-8 weeks
8-12 weeks
Within days
4-12 weeks
4-8 weeks
Dietary supplements for dysmenorrhoea
The Cochrane database of systematic reviews (2016) · Meta analysis · n=3101
Supplements versus other supplementsThere was no evidence of a difference in effectiveness between ginger and zinc sulphate (MD 0.02 points, 95% CI -0.58 to 0.62; one RCT, 101 women).
The effect of flour-based foods intake in the reduction of cardiometabolic risk: A systematic review
Critical reviews in food science and nutrition (2024) · Systematic review
Chia flour, green banana flour, soy flour, and fenugreek powder showed improvements in blood pressure measurements.
Effect of Fenugreek on Hyperglycemia: A Systematic Review and Meta-Analysis
Medicina (Kaunas, Lithuania) (2023) · Meta analysis · n=894
The mean difference with 95% confidence intervals (CI) was calculated to represent the analysis.
Maternal Iodine Status and Birth Outcomes: A Systematic Literature Review and Meta-Analysis
Nutrients (2023) · Meta analysis · n=42269
Birth weight was similar between UIC ≥ 150 μg/L and <150 μg/L (difference = 30 g, 95% CI −22 to 83, p = 0.3, n = 13, I2 = 89%) with no evidence of linear trend (4 g per 50 μg/L, −3 to 10, p = 0.2, n = 12, I2 = 80%).
Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders
The Cochrane database of systematic reviews (2019) · Meta analysis · n=4317
This is equivalent to an increase of 38.32 µg/L (95% CI 24.03 to 52.61 µg/L).
Systematic review and meta-analysis of iodine nutrition in modern vegan and vegetarian diets
The British journal of nutrition (2023) · Meta analysis · n=4421
Vegan diets had the poorest iodine intake (17·3 µg/d) and were strongly associated with lower iodine intake (P = < 0·001) compared with omnivorous diets.
Multiple meta-analyses show modest but consistent reductions in fasting blood glucose. Effects appear stronger in diabetic populations. Conservative estimates given heterogeneity in study designs and extract standardization.
Based on meta-analyses showing urinary iodine concentration increases with supplementation. Effects only meaningful in iodine-deficient populations. Excessive intake (>300mcg) may increase thyroid cancer risk. Most studies used potassium iodide; kelp-derived forms have variable bioavailability.
AI-estimated from published studies. Interpret as directional guidance.
Fenugreek has a higher evidence score (7.5/10 vs 9/10) and wins in 2 of 3 categories.
For boost daily energy, Iodine has a higher relevance score (95 vs 48).
No known interactions between Fenugreek and Iodine have been documented in our database. However, always consult a healthcare provider before combining supplements.