Loading…
We use essential cookies (authentication, your saved goals/stack) by default. With your permission we’ll also enable privacy-respecting analytics (Vercel Web Analytics, anonymous load-time metrics) and error-replay diagnostics (Sentry — DOM snapshots only when an error fires) so we can fix bugs faster. Learn more about cookies
Head-to-head evidence comparison — which supplement is right for you?
GABA vs Passionflower: Passionflower has the stronger overall evidence (5.5 vs 4/10); they're alternatives for reduce anxiety & stress — the best pick depends on your goals. Take the 60-second quiz for a pick tailored to your goals.
Passionflower wins 2 of 3 categories. Both are solid choices — the best pick depends on your specific goals.
Verdict
Too few graded studies
Top outcomes
Verdict
Too few graded studies
0 of 1 studies with measurable effects showed benefit.
Top outcomes
Shared outcomes (2)
Outcomes where both GABA and Passionflower have evidence — compare verdict strength side-by-side.
250-300 mg (the one cited trial that states its dose used 300 mg a day). Label ranges go up to 750 mg, above that dose.
30-60 minutes before desired effect, Before bed for sleep, Before stressful events for anxiety
Capsules or powder
250-500mg extract (or 2g dried herb) (a typical label dose, the cited trials state their doses only as drops of liquid extract or a cup of tea, not in mg)
For anxiety: as needed, For sleep: 30-60 minutes before bed
Standardized extract capsules
30-60 minutes
30-60 minutes
30-60 minutes
30 min - 2 hours
30-60 minutes
30-60 minutes
Herbal Remedies and Their Possible Effect on the GABAergic System and Sleep
Nutrients (2021) · Systematic review
A systematic analysis of studies on how various herbal medicines act on GABA receptor subtypes in the context of sleep. It reviews mechanisms, not trials of GABA supplements.
Effect of Probiotics on the Symptomatology of Autism Spectrum Disorder and/or Attention Deficit/Hyperactivity Disorder in Children and Adolescents: Pilot Study
Research on child and adolescent psychopathology (2025) · Rct · n=80
80 children aged 5 to 16 with ADHD (38) or autism (42) took a probiotic (Lactiplantibacillus plantarum and Levilactobacillus brevis, strains linked to dopamine and GABA production) or placebo for 12 weeks. No GABA was given.
GABA Supplementation, Increased Heart-Rate Variability, Emotional Response, Sleep Efficiency and Reduced Depression in Sedentary Overweight Women Undergoing Physical Exercise: Placebo-Controlled, Randomized Clinical Trial
Journal of dietary supplements (2024) · Rct · n=30
30 sedentary women with overweight or obesity doing physical exercise took GABA 200 mg or placebo once daily for 90 days.
Herbal Remedies and Their Possible Effect on the GABAergic System and Sleep
Nutrients (2021) · Systematic review
Gamma-aminobutyric acid (GABA) is an inhibitory neurotransmitter that plays a major role in controlling different vigilance states.
Passiflora incarnata in Neuropsychiatric Disorders-A Systematic Review
Nutrients (2020) · Systematic review
The systematic review included nine clinical trials, lasting from one day up to 30 days, in adults.
Herbal medicine for depression and anxiety: A systematic review with assessment of potential psycho-oncologic relevance
Phytotherapy research : PTR (2018) · Systematic review
Overall, 45% of studies reported positive findings with fewer adverse effects compared with conventional medications.
Passionflower has a higher evidence score (5.5/10 vs 4/10) and wins in 2 of 3 categories.
For reduce anxiety & stress, Passionflower has a higher relevance score (85 vs 75).
No documented interaction was found in the data searched. This does not establish that this exact combination is safe.
The right pick depends on your goals. Answer a few quick questions for a personalised recommendation — or dig into the full evidence on each.