Loading…
We use essential cookies (authentication, your saved goals/stack) by default. With your permission we'll also enable privacy-respecting analytics (Vercel Web Analytics, anonymous load-time metrics) and error-replay diagnostics (Sentry — DOM snapshots only when an error fires) so we can fix bugs faster. Learn more
Head-to-head evidence comparison — which supplement is right for you?
Riboflavin wins 1 of 3 categories. Both are solid choices — the best pick depends on your specific goals.
Verdict
Probably helps
7 of 11 studies with measurable effects showed benefit.
Top outcomes
Verdict
Likely helps
7 of 9 studies with measurable effects showed benefit.
Top outcomes
Shared outcomes (1)
Outcomes where both Ginkgo Biloba and Riboflavin have evidence — compare verdict strength side-by-side.
120-240mg standardized extract
With meals, Split into 2-3 doses
Standardized extract capsules (EGb 761)
25-50mg for general health; 400mg for migraine prevention
With food for better absorption, Morning with other B vitamins
Riboflavin or Riboflavin-5-Phosphate (R-5-P)
4-6 weeks
4-8 weeks
First week
3 months
2-4 weeks
Immediate
Can We Use Ginkgo biloba Extract to Treat Alzheimer's Disease? Lessons from Preclinical and Clinical Studies
Cells (2022) · Meta analysis · n=2100
GBE was shown to reduce the escape latencies in several studies, in both rats and mice (I2 > 70%, p < 0.005).
Beneficial effects of Ginkgo biloba leaf extract on inflammatory markers: A systematic review and meta-analysis of the clinical trials
Phytotherapy research : PTR (2022) · Meta analysis · n=1104
In the meta-analysis, the weighted mean differences (WMD) in change for serum CRP were -1.5 mg/L (95% CI: -2.16, -0.85, p < 0.001).
Miscellaneous treatments for antipsychotic-induced tardive dyskinesia
The Cochrane database of systematic reviews (2018) · Meta analysis · n=1278
Studies were primarily of short (three to six6 weeks) duration with small samples size (10 to 157 participants), and most (61%) were published more than 20 years ago.
Effect of Vitamin B2 supplementation on migraine prophylaxis: a systematic review and meta-analysis
Nutritional neuroscience (2022) · Meta analysis · n=673
Vitamin B2 supplementation significantly decreased migraine days (p = .005, I2 = 89%), duration (p = .003, I2 = 0), frequency (p = .001, I2 = 65%), and pain score (p = .015, I2 = 84%).
Effects of selected dietary supplements on migraine prophylaxis: A systematic review and dose-response meta-analysis of randomized controlled trials
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2025) · Meta analysis
In adults, compared with placebo, these supplements did not significantly affect other outcomes, and omega-3 supplementation did not yield a statistically significant reduction in any of these outcomes.
Riboflavin supplements for blood pressure lowering in adults
The Cochrane database of systematic reviews (2025) · Meta analysis · n=320
The evidence for the effect of oral riboflavin supplements on systolic and diastolic blood pressure is very uncertain.
Based on multiple meta-analyses including 2100+ participants showing benefits in mild dementia and memory. Effects modest and primarily in older adults or those with existing cognitive decline. Standardized extract (EGb 761) preferred.
Based on meta-analysis showing significant reduction in migraine frequency, days, duration, and pain score. High heterogeneity (I2=65-89%) in pooled analyses suggests variable individual responses. Most studies used 400mg daily dose.
AI-estimated from published studies. Interpret as directional guidance.
Riboflavin has a higher evidence score (9/10 vs 9/10) and wins in 1 of 3 categories.
No known interactions between Ginkgo Biloba and Riboflavin have been documented in our database. However, always consult a healthcare provider before combining supplements.