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Head-to-head evidence comparison — which supplement is right for you?
Saccharomyces Boulardii wins 1 of 3 categories. Both are solid choices — the best pick depends on your specific goals.
Verdict
Likely helps
7 of 9 studies with measurable effects showed benefit.
Top outcomes
Verdict
Likely helps
13 of 15 studies with measurable effects showed benefit.
Top outcomes
Shared outcomes (1)
Outcomes where both Green Tea Extract and Saccharomyces Boulardii have evidence — compare verdict strength side-by-side.
250-500mg EGCG (or 500-1000mg green tea extract)
With meals, Morning or pre-exercise
Standardized extract (45-50% EGCG)
250-500mg (5-10 billion CFU) daily
With or without food, At least 2 hours away from antifungals
Capsules (lyophilized)
Acute and 4-8 weeks
Acute
30-60 minutes
During use
1-3 days
1-2 weeks
Green tea (Camellia sinensis) for the prevention of cancer
The Cochrane database of systematic reviews (2020) · Meta analysis · n=1795
For incident prostate cancer, the summary risk ratio (RR) in the green tea-supplemented participants was 0.50 (95% confidence interval (CI) 0.18 to 1.36), based on three studies and involving 201 participants (low-certainty evidence).
Impact of flavan-3-ols on blood pressure and endothelial function in diverse populations: a systematic review and meta-analysis of randomized controlled trials
European journal of preventive cardiology (2025) · Meta analysis · n=5205
Flavan-3-ol interventions included epicatechin, epigallocatechin-gallate, cocoa products, tea, grape extract, and apples delivering 586 mg (95% CI 510, 662) total flavan-3-ols.
The effects of green tea extract supplementation on body composition, obesity-related hormones and oxidative stress markers: a grade-assessed systematic review and dose-response meta-analysis of randomised controlled trials
The British journal of nutrition (2024) · Meta analysis · n=3802
Pooled effect sizes indicated that BM, BFP, BMI and MDA significantly reduced following GTE supplementation.
Efficacy and safety of Saccharomyces boulardii as an adjuvant therapy for the eradication of Helicobacter pylori: a meta-analysis
Frontiers in cellular and infection microbiology (2025) · Meta analysis · n=5036
S. boulardii supplementation in traditional eradication therapy significantly improves the H. pylori eradication rate and reduces the total adverse effects and incidence of diarrhea, bloating, constipation, and nausea.
Probiotics for treating acute infectious diarrhoea
The Cochrane database of systematic reviews (2020) · Meta analysis · n=12127
Effect size was similar in the sensitivity analysis and marked heterogeneity persisted.
The use of probiotics and prebiotics in decolonizing pathogenic bacteria from the gut; a systematic review and meta-analysis of clinical outcomes
Gut microbes (2024) · Meta analysis · n=2871
This review aims to analyze available evidence from human-controlled trials to determine the effect size of probiotic interventions in decolonizing AMR pathogenic bacteria from the gut.
Based on meta-analysis showing 9.29 mg/dl LDL reduction with 107-856 mg/d EGCG. Optimal cardiovascular benefits observed at 400-500 mg/day. Take with food to reduce GI side effects.
Based on multiple meta-analyses showing 1.1-1.6 day reduction in diarrhea duration. Effect size appears to plateau at standard therapeutic doses. Limited data on doses above 20 billion CFU.
AI-estimated from published studies. Interpret as directional guidance.
Saccharomyces Boulardii has a higher evidence score (9/10 vs 9/10) and wins in 1 of 3 categories.
For reduce inflammation, Saccharomyces Boulardii has a higher relevance score (90 vs 85).
No known interactions between Green Tea Extract and Saccharomyces Boulardii have been documented in our database. However, always consult a healthcare provider before combining supplements.