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Head-to-head evidence comparison — which supplement is right for you?
Iodine vs Potassium: Potassium has the stronger overall evidence (8.5 vs 8.5/10); they're alternatives for boost daily energy — the best pick depends on your goals. Take the 60-second quiz for a pick tailored to your goals.
Potassium wins 1 of 3 categories. Both are solid choices — the best pick depends on your specific goals.
Verdict
Limited support
1 of 4 studies with measurable effects showed benefit.
Top outcomes
Verdict
Probably helps
2 of 3 studies with measurable effects showed benefit.
Top outcomes
150-300mcg for maintenance; higher only if deficient under supervision
Any time with food
Potassium iodide (most common and studied)
Supplements commonly provide 99 mg per serving, and food provides more (no cited trial states the dose it used). No upper limit is established, so no maximum is stored. That is not a statement that larger amounts are safe.
With food to reduce GI upset, Spread throughout day, During/after exercise for athletes
Potassium Citrate or Potassium Gluconate
and 2 more not shown
and 10 more not shown
4-12 weeks
4-8 weeks
2-4 weeks
1-2 weeks
Long-term
With excess or kidney issues
Maternal Iodine Status and Birth Outcomes: A Systematic Literature Review and Meta-Analysis
Nutrients (2023) · Meta analysis · n=42269
Birth weight was similar between UIC ≥ 150 μg/L and <150 μg/L (difference = 30 g, 95% CI −22 to 83, p = 0.3, n = 13, I2 = 89%) with no evidence of linear trend (4 g per 50 μg/L, −3 to 10, p = 0.2, n = 12, I2 = 80%).
Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders
The Cochrane database of systematic reviews (2019) · Meta analysis · n=4317
This is equivalent to an increase of 38.32 µg/L (95% CI 24.03 to 52.61 µg/L).
Systematic review and meta-analysis of iodine nutrition in modern vegan and vegetarian diets
The British journal of nutrition (2023) · Meta analysis · n=4421
Vegan diets had the poorest iodine intake (17·3 µg/d) and were strongly associated with lower iodine intake (P = < 0·001) compared with omnivorous diets.
Effect of changes in potassium intake on blood pressure: a dose–response meta-analysis of randomized clinical trials (2000–2024)
Clinical Kidney Journal (2025) · Meta analysis
Our meta-analysis included 10 RCTs, comprising 4 studies on subjects without hypertension and 6 studies on subjects with hypertension.
Magnesium and Potassium Supplementation for Systolic Blood Pressure Reduction in the General Normotensive Population: A Systematic Review and Subgroup Meta-Analysis for Optimal Dosage and Treatment Length
Nutrients (2024) · Meta analysis
Both supplements demonstrated greater reductions in SBP for the general population at lower dosages and longer treatment durations.
Sex-specific associations between sodium and potassium intake and overall and cause-specific mortality: a large prospective U.S. cohort study, systematic review, and updated meta-analysis of cohort studies
BMC medicine (2024) · Meta analysis · n=416104
Prospective analysis of 237,036 men and 179,068 women in the NIH-AARP Diet and Health Study, plus an updated meta-analysis of cohort studies.
Potassium has a higher evidence score (8.5/10 vs 8.5/10) and wins in 1 of 3 categories.
For boost daily energy, Iodine has a higher relevance score (95 vs 50).
No documented interaction was found in the data searched. This does not establish that this exact combination is safe.
Selenium helps; iodine can WORSEN Hashimoto’s. The honest take on "thyroid support".
What’s safe while nursing, the truth about milk-supply herbs, and what to avoid (it passes into milk).
Commonly recommended vs ask-your-clinician vs avoid — a general, safety-first overview.
Who actually needs electrolytes (and who doesn’t), what matters (sodium), and LMNT vs alternatives.
The right pick depends on your goals. Answer a few quick questions for a personalised recommendation — or dig into the full evidence on each.