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Head-to-head evidence comparison — which supplement is right for you?
Lavender and Passionflower are closely matched across evidence, studies, and safety.
Verdict
Mostly mechanism / observational
Top outcomes
Verdict
Likely helps
4 of 4 studies with measurable effects showed benefit.
Top outcomes
Shared outcomes (2)
Outcomes where both Lavender and Passionflower have evidence — compare verdict strength side-by-side.
80 mg oral Silexan daily OR aromatherapy inhalation 30–60 min sessions
Evening before bed for sleep and anxiety, Acute use before stressful procedures or events
Oral Silexan capsule (80 mg) for systemic/psychiatric use
250-500mg extract (or 2g dried herb)
For anxiety: as needed, For sleep: 30-60 minutes before bed
Standardized extract capsules
1–4 weeks
1–3 weeks
4–8 weeks
Acute to 2 weeks
30 min - 2 hours
30-60 minutes
30-60 minutes
Effects of lavender on anxiety: A systematic review and meta-analysis.
Phytomedicine : international journal of phytotherapy and phytopharmacology (2019) · Meta analysis
Meta-analysis confirmed significant anxiolytic effects of lavender across multiple administration routes
Efficacy of Silexan in patients with anxiety disorders: a meta-analysis of randomized, placebo-controlled trials.
European archives of psychiatry and clinical neuroscience (2023) · Meta analysis
Silexan 80 mg/day was significantly superior to placebo in reducing Hamilton Anxiety Rating Scale (HAMA) total scores
Efficacy of Silexan in subthreshold anxiety: meta-analysis of randomised, placebo-controlled trials.
European archives of psychiatry and clinical neuroscience (2019) · Meta analysis
Silexan 80 mg/day significantly reduced HAMA scores compared to placebo in subthreshold anxiety
Herbal Remedies and Their Possible Effect on the GABAergic System and Sleep
Nutrients (2021) · Systematic review
Gamma-aminobutyric acid (GABA) is an inhibitory neurotransmitter that plays a major role in controlling different vigilance states.
Passiflora incarnata in Neuropsychiatric Disorders-A Systematic Review
Nutrients (2020) · Systematic review
Passiflora incarnata may be helpful in treating some symptoms in neuropsychiatric patients.
Herbal medicine for depression and anxiety: A systematic review with assessment of potential psycho-oncologic relevance
Phytotherapy research : PTR (2018) · Systematic review
Overall, 45% of studies reported positive findings with fewer adverse effects compared with conventional medications.
Based on meta-analysis of 198 subjects noting insufficient RCT data for definitive conclusions. Effectiveness limited by small sample sizes and study quality limitations. Drowsiness is primary dose-limiting side effect.
AI-estimated from published studies. Interpret as directional guidance.
Both Lavender and Passionflower are closely matched — the best choice depends on your specific health goals.
For reduce anxiety & stress, Lavender has a higher relevance score (90 vs 85).
No known interactions between Lavender and Passionflower have been documented in our database. However, always consult a healthcare provider before combining supplements.