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Head-to-head evidence comparison — which supplement is right for you?
Magnesium vs Yohimbine: Magnesium has the stronger overall evidence (8.5 vs 5/10); the best pick depends on your goals. Take the 60-second quiz for a pick tailored to your goals.
Magnesium wins 3 of 3 categories. Both are solid choices — the best pick depends on your specific goals.
Verdict
Likely helps
10 of 13 studies with measurable effects showed benefit.
Top outcomes
Verdict
Mostly mechanism / observational
Top outcomes
200-350mg elemental magnesium daily
Evening for sleep/relaxation (glycinate), Morning for energy (malate), Anytime (citrate)
Depends on goal - see notes
Standardized yohimbine HCl ~0.2 mg/kg (roughly 5-15 mg) up to 1-2x daily; start at the lowest dose, ideally fasted for the fat-loss effect. Never combine with other stimulants.
morning
Standardized yohimbine HCl (known dose)
and 4 more not shown
and 2 more not shown
1-2 weeks
1-2 weeks
1 week
Immediate
3-8 weeks
2-8 weeks
Acute
Acute
Magnesium supplementation in pregnancy
The Cochrane database of systematic reviews (2014) · Meta analysis · n=9090
Women receiving magnesium were significantly less likely to require hospitalisation during pregnancy (RR 0.65, 95% CI 0.48 to 0.86; three trials, 1158 women).Of the 10 trials included in the review, only two were judged to be of high quality overall.
Magnesium Supplementation and Blood Pressure: A Systematic Review and Meta-Analysis
Hypertension (2025) · Meta analysis · n=2709
38 RCTs with 2709 participants analyzed
Magnesium and Potassium Supplementation for Systolic Blood Pressure Reduction in the General Normotensive Population: A Systematic Review and Subgroup Meta-Analysis for Optimal Dosage and Treatment Length
Nutrients (2024) · Meta analysis
Both supplements demonstrated greater reductions in SBP for the general population at lower dosages and longer treatment durations.
Yohimbine for erectile dysfunction: a systematic review and meta-analysis of randomized clinical trials.
The Journal of urology (1998) · Meta analysis
Meta-analysis of seven placebo-controlled RCTs of yohimbine monotherapy for erectile dysfunction
Yohimbine as a treatment for erectile dysfunction: A systematic review and meta-analysis.
Turkish journal of urology (2021) · Meta analysis
Systematic review and meta-analysis of eight RCTs comparing yohimbine to placebo for ED
Yohimbine: the effects on body composition and exercise performance in soccer players.
Research in sports medicine (2006) · Rct · n=20
Randomized placebo-controlled trial in 20 elite male soccer players, 20 mg/day for 21 days
Based on meta-analysis of 38 RCTs with 2709 participants showing -7.68 mmHg reduction in hypertensive individuals. Effects are greatest in those with hypomagnesemia. Limited evidence in normotensive populations.
AI-estimated from published studies. Interpret as directional guidance.
Magnesium has a higher evidence score (8.5/10 vs 5/10) and wins in 3 of 3 categories.
No known interactions between Magnesium and Yohimbine have been documented in our database. However, always consult a healthcare provider before combining supplements.
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The right pick depends on your goals. Answer a few quick questions for a personalised recommendation — or dig into the full evidence on each.