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Head-to-head evidence comparison — which supplement is right for you?
Potassium vs Yohimbine: Potassium has the stronger overall evidence (8.5 vs 5/10); the best pick depends on your goals. Take the 60-second quiz for a pick tailored to your goals.
Potassium wins 3 of 3 categories. Both are solid choices — the best pick depends on your specific goals.
Verdict
Probably helps
2 of 3 studies with measurable effects showed benefit.
Top outcomes
Verdict
Too few graded studies
Top outcomes
Supplements commonly provide 99 mg per serving, and food provides more (no cited trial states the dose it used). No upper limit is established, so no maximum is stored. That is not a statement that larger amounts are safe.
With food to reduce GI upset, Spread throughout day, During/after exercise for athletes
Potassium Citrate or Potassium Gluconate
Standardized yohimbine HCl ~0.2 mg/kg (roughly 5-15 mg) up to 1-2x daily; start at the lowest dose, ideally fasted for the fat-loss effect. Never combine with other stimulants.
Morning
Standardized yohimbine HCl (known dose)
and 10 more not shown
and 2 more not shown
2-4 weeks
1-2 weeks
Long-term
With excess or kidney issues
3-8 weeks
2-8 weeks
Acute
Acute
Effect of changes in potassium intake on blood pressure: a dose–response meta-analysis of randomized clinical trials (2000–2024)
Clinical Kidney Journal (2025) · Meta analysis
Our meta-analysis included 10 RCTs, comprising 4 studies on subjects without hypertension and 6 studies on subjects with hypertension.
Magnesium and Potassium Supplementation for Systolic Blood Pressure Reduction in the General Normotensive Population: A Systematic Review and Subgroup Meta-Analysis for Optimal Dosage and Treatment Length
Nutrients (2024) · Meta analysis
Both supplements demonstrated greater reductions in SBP for the general population at lower dosages and longer treatment durations.
Sex-specific associations between sodium and potassium intake and overall and cause-specific mortality: a large prospective U.S. cohort study, systematic review, and updated meta-analysis of cohort studies
BMC medicine (2024) · Meta analysis · n=416104
Prospective analysis of 237,036 men and 179,068 women in the NIH-AARP Diet and Health Study, plus an updated meta-analysis of cohort studies.
Yohimbine for erectile dysfunction: a systematic review and meta-analysis of randomized clinical trials.
The Journal of urology (1998) · Meta analysis
Meta-analysis of seven placebo-controlled RCTs of yohimbine monotherapy for erectile dysfunction
Yohimbine as a treatment for erectile dysfunction: A systematic review and meta-analysis.
Turkish journal of urology (2021) · Meta analysis
Systematic review and meta-analysis of eight RCTs comparing yohimbine with placebo or no treatment for erectile dysfunction.
Yohimbine: the effects on body composition and exercise performance in soccer players.
Research in sports medicine (2006) · Rct · n=20
Randomized placebo-controlled trial in 20 elite male soccer players, 20 mg/day for 21 days
Potassium has a higher evidence score (8.5/10 vs 5/10) and wins in 3 of 3 categories.
No documented interaction was found in the data searched. This does not establish that this exact combination is safe.
The right pick depends on your goals. Answer a few quick questions for a personalised recommendation — or dig into the full evidence on each.