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Head-to-head evidence comparison — which supplement is right for you?
Rosuvastatin (Crestor) vs Telmisartan: Rosuvastatin (Crestor) has the stronger overall evidence (4.5 vs 4.3/10); they're alternatives for support heart health — the best pick depends on your goals. Take the 60-second quiz for a pick tailored to your goals.
Rosuvastatin (Crestor) wins 2 of 3 categories. Both are solid choices — the best pick depends on your specific goals.
Verdict
Mostly mechanism / observational
Top outcomes
Verdict
Mostly mechanism / observational
Top outcomes
Shared outcomes (2)
Outcomes where both Rosuvastatin (Crestor) and Telmisartan have evidence — compare verdict strength side-by-side.
5–20 mg once daily (up to 40 mg in selected high-risk patients), titrated to LDL/ApoB targets — under a clinician. A prescription drug; not a self-directed supplement regimen.
any
Oral tablet (rosuvastatin 5–20 mg)
Approved antihypertensive dosing is 20–80 mg once daily; the metabolic/PPARγ effects are most evident at the higher 80 mg (and study) doses, under a clinician. Not an approved metabolic or longevity regimen; blood pressure, kidney function, and potassium should be monitored.
morning
Oral tablet (telmisartan)
2–4 weeks
Months to years
1–2 years
Throughout use
Months to years
Weeks to months
Years
Throughout use
Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein.
The New England journal of medicine (2008) · Rct · n=17802
JUPITER randomized placebo-controlled primary-prevention trial (~17,800 participants with normal LDL but elevated hsCRP)
Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials.
Lancet (London, England) (2010) · Meta analysis
Meta-analysis of ~170,000 participants across 26 randomized statin trials
Effect of very high-intensity statin therapy on regression of coronary atherosclerosis: the ASTEROID trial.
JAMA (2006) · Open label · n=507
ASTEROID open-label IVUS trial (507 enrolled; 349 with evaluable serial imaging)
Telmisartan, ramipril, or both in patients at high risk for vascular events.
The New England journal of medicine (2008) · Rct · n=25620
ONTARGET randomized 25,620 high-vascular-risk patients to ramipril, telmisartan, or both
Renal outcomes with telmisartan, ramipril, or both, in people at high vascular risk (the ONTARGET study): a multicentre, randomised, double-blind, controlled trial.
Lancet (London, England) (2008) · Rct · n=25620
Prespecified ONTARGET renal analysis of the same 25,620 patients
Effects of the angiotensin-receptor blocker telmisartan on cardiovascular events in high-risk patients intolerant to angiotensin-converting enzyme inhibitors: a randomised controlled trial.
Lancet (London, England) (2008) · Rct · n=5926
TRANSCEND randomized 5,926 ACE-inhibitor-intolerant high-risk patients to telmisartan or placebo
Rosuvastatin (Crestor) has a higher evidence score (4.5/10 vs 4.3/10) and wins in 2 of 3 categories.
For support heart health, Rosuvastatin (Crestor) has a higher relevance score (78 vs 66).
No known interactions between Rosuvastatin (Crestor) and Telmisartan have been documented in our database. However, always consult a healthcare provider before combining supplements.
The right pick depends on your goals. Answer a few quick questions for a personalised recommendation — or dig into the full evidence on each.