Compare Supplements

Side-by-side comparison of 2 supplements

Age9.0

Aged Garlic Extract

High safety

Spd8.0

Spermidine

High safety

Evidence

Evidence Score9/10

Studies: 42

Meta-analyses: 5

Evidence Score8/10

Studies: 23

Meta-analyses: 2

Outcome Grades

Reduce inflammationA

Healthy agingB

Reduce inflammationB

Healthy agingA

A-F grade per outcome, combining overall evidence with goal-specific relevance. A = strong evidence; F = insufficient. Hover a badge for details.

Dosage & timing

Dosage:

1200mg

Best Time:

With meals · with food

Take with food

Form:

Kyolic Aged Garlic Extract (most studied)

Dosage:

4mg

Best Time:

Morning · with food (preferred)

Can take on empty stomach

Form:

Wheat germ extract standardized to spermidine

What you'll notice

📉 Blood Pressure Reduction65%

8-12 weeks

❤️ Arterial Health55%

12+ weeks

🛡️ Immune Support50%

4-8 weeks

🔄 Cellular Renewal25%

Ongoing

❤️ Cardiovascular Benefits50%

Ongoing

Safety

High safety

Contraindications:

Before surgery (stop 2 weeks prior)

Drug Interactions:

Blood thinners (Warfarin, aspirin)
HIV medications (saquinavir)
Blood pressure medications

Side Effects:

GI upsetGarlic breath (mild)

High safety

Contraindications:

Cancer (theoretical concern — polyamines may support cancer cell growth)

Drug Interactions:

No significant interactions known

Side Effects:

Mild GI effects

Works well with

complementary

complementary

complementary

complementary

How they work together

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