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Probiotics Research Archive — Page 8 of 76 | SupStack
Probiotics Research Archive
Studies 1301–1350 of 4743, newest first
The 1000 most recent studies, with the evidence summary, filters and search, are on the main research page. This archive lists the rest, 50 per page. Back to the main research page
1301Meta-Analysis2023
Zhu J, Pitre T, Ching C, Zeraatkar D, Gruchy S · PLoS One (2023)
No plain-language summary recorded for this citation — open the paper to read its abstract.
1304Gut microbiome restoration in Alzheimer's diseaseReview2023
Thakkar A et al. · Naunyn-Schmiedeberg's archives of pharmacology (2023)
It also highlights challenges involved in large-scale manufacturing and quality control of probiotic formulations.
Restoration of levels of beneficial microorganisms in the gut has demonstrated promising effects in AD in pre-clinical and clinical studies.
The current review enlists the important beneficial microbial species present in the gut, the effect of their metabolites on CNS, mechanisms involved in dysbiosis related to AD and the beneficial effects of probiotics on AD.
It also highlights challenges involved in large-scale manufacturing and quality control of probiotic formulations.
Lewandowska-Pietruszka Z et al. · International journal of molecular sciences (2023)
Future investigations may unveil complex mechanisms linking the gut microbiota to ASD, ultimately enhancing the quality of life for affected individuals.
↑81 %↑78 %
ASD children exhibit increased Firmicutes (36-81%) and Pseudomonadota (78%) and decreased Bacteroidetes (56%).
The Bacteroidetes to Firmicutes ratio tends to be lower (56%) compared to children without ASD, which correlates with behavioral and gastrointestinal abnormalities.
Probiotics, particularly Lactobacillus, Bifidobacterium, and Streptococcus strains, show promise in alleviating behavioral and gastrointestinal symptoms (66%).
1309Oral health conditions including dental caries, periodontal diseases, and halitosisReview2023
Homayouni Rad A et al. · Frontiers in cellular and infection microbiology (2023)
In this review, while investigating the effect of different strains of probiotics Lactobacillus and Bifidobacteria on oral diseases, including dental caries, candida yeast infections, periodontal diseases, and halitosis, we have also discussed postbiotics as novel non-living biological compounds derived from probiotics.
Also, Streptococcus mutans is considered the most important caries-causing species.
It is expected that probiotics, as they adjust the intestinal microbiota and reduce the number of pathogenic bacteria in the human intestine, can exert their health-giving effects, especially the anti-pathogenic effect, in the oral cavity, which is part of the human gastrointestinal tract.
Therefore, numerous in vitro and in vivo studies have been conducted on the role of probiotics in the prevention of tooth decay.
1313Immunomodulatory effects in breast cancer treatmentReview2023
Summer M et al. · Archives of microbiology (2023)
Last, but not the least, current review concludes the use of probiotics in the treatment of breast cancer through various mechanisms and future recommendations for molecular basis studies.
In Vivo and In Vitro studies under breast cancer research regarding probiotics are mechanistically explained.
The current review systematically explains the immunomodulatory role of probiotics to prevent breast cancer.
Last, but not the least, current review concludes the use of probiotics in the treatment of breast cancer through various mechanisms and future recommendations for molecular basis studies.
Buhaș MC et al. · International journal of molecular sciences (2023)
Furthermore, in the 15/42 patients in the intervention group who received gut microbiota analysis, the gut microbiota changed favorably following 12 weeks of probiotic and prebiotic supplementation, with a shift towards an anti-inflammatory profile.
12w medium
In total, 63 patients were evaluated, with the first 42 enrolled patients assigned to the intervention group and the next 21 assigned to the control group (2:1 ratio; non-randomized).
Furthermore, in the 15/42 patients in the intervention group who received gut microbiota analysis, the gut microbiota changed favorably following 12 weeks of probiotic and prebiotic supplementation, with a shift towards an anti-inflammatory profile.
Shannon diversity index showed that after 8-weeks amid VC, a shift in microbial community compositional changes occurred in the high vaginal region at both genus (P=0.025) and species (P=0.044) levels, where the administration of probiotic prevented such a shift.
These changes were mainly attributed to a decreased in abundance of Lactobacillus (P=0.042) accompanied by increased abundance of Prevotella (P=0.002) and Atopobium (P=0.002) in the placebo group while the probiotic group remained unchanged over time.
The administration of probiotics also prevented a reduced abundance of faecal phylum Firmicutes after 8-weeks as seen in the placebo group (P<0.0001), which also showed reduction at subsequent taxonomic levels of class, family, genera and species.
Huang YY et al. · Molecules (Basel, Switzerland) (2023)
The anti-allergic role of probiotics in the function and metabolism of the gastrointestinal tract has been comprehensively explored to furnish insights for relieving food allergy symptoms and preventing food allergy.
Multiple pieces of evidence reveal a significant disruptive effect of probiotics on food allergy pathology and progression mechanisms.
Thus, this review describes the allergenic proteins as an entry point and briefly describes the application of probiotics in allergenic foods.
Then, the role of probiotics in preventing and curing allergic diseases by regulating human immunity through intestinal flora and intestinal barrier, modulating host immune active cells, and improving host amino acid metabolism are described in detail.
In conclusion, this study presents evidence supporting the benefits of multi-strain probiotics in enhancing BDNF, ameliorating inflammation and oxidative stress in AD patients.
✓p=0.005↑3612w medium
After 12 weeks of intervention, the treatment group demonstrated a 36% increase in serum brain-derived neurotrophic factor (BDNF) (* p = 0.005), a reduction in IL-1β (* p = 0.041), and an increase in antioxidant superoxide dismutase (SOD) (* p = 0.012).
A trend toward less cognitive deterioration was observed, but not statistically significant.
No significant change was found in the active control group.