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Probiotics Research Archive — Page 9 of 76 | SupStack
Probiotics Research Archive
Studies 1351–1400 of 4743, newest first
The 1000 most recent studies, with the evidence summary, filters and search, are on the main research page. This archive lists the rest, 50 per page. Back to the main research page
1351Meta-Analysis2023
Liu L, Wang A, Shi H, Tao H, Nahata MC · Clin Nutr (2023)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Jach ME et al. · Molecules (Basel, Switzerland) (2023)
For the effectiveness of antidepressant therapy, psychobiotics should be administered at a dose higher than 1 billion CFU/day for at least 8 weeks.
↑8 weeks
However, restoration of the intestinal microbiota and functions of the gut-brain axis via using probiotics, their metabolites, prebiotics, and healthy diet may alleviate depressive symptoms.
Administration of probiotics labeled as psychobiotics and their metabolites as metabiotics, especially as an adjuvant to antidepressants, improves mental disorders.
It is a new approach to the prevention, management, and treatment of mental and emotional illnesses, particularly major depressive disorder and metabolic depression.
1361FEV1 in asthma patientsMeta-Analysisn=1,1012023
Xie Q et al. · Nutricion hospitalaria (2023)
Conclusion: the use of probiotics in patients with asthma can improve lung inflammation and asthma symptoms, reduce the number of asthma attacks, and have no effect on lung function.
0.11 [-0.05, 0.26]
Meta-analysis was performed using Revman 5.4 software and the combined effect was evaluated by odds ratio (OR) or mean difference (MD) and 95 % confidence interval (CI).
There was no significant difference in forced expiratory volume in the first second (FEV1) (MD = 0.11, 95 % CI: -0.05, 0.26) and FEV1/FVC (%) (MD = 0.32, 95 % CI: -1.48, 2.12).
Results: a total of ten references were included, all of which were randomized controlled studies, and a total of 1,101 people were investigated.
Gao J et al. · European journal of gastroenterology & hepatology (2023)
Finally, we conclude that microbiome therapies were more effective in improving MHE and preventing progression to OHE, reducing the frequency of SAEs, and decreasing ammonia levels, NCT level, and hospitalization rates when compared to placebo/no treatment.
↑95 %
Meta-analysis was performed to calculate pooled odds ratios (ORs) with corresponding 95% confidence intervals (CIs).
Twenty-one studies met our inclusion criteria (N = 1746 participants).
Finally, we conclude that microbiome therapies were more effective in improving MHE and preventing progression to OHE, reducing the frequency of SAEs, and decreasing ammonia levels, NCT level, and hospitalization rates when compared to placebo/no treatment.
The possibility of probiotic immunotherapy as a "living adjuvant" to CAR treatment and checkpoint blockade resistance is actively being investigated.
The first step in developing probiotics for immunotherapy is identifying helpful or harmful bacteria down to the strain level.
The gut microbiome's heterogeneity before and during treatment is also being investigated to determine microbial strains that are important for immunotherapy.
Moreover, Dietary fiber intake, prebiotic supplementation and fecal microbiota transplantation (FMT) were found to enhance intratumoral CD8+ T cell to T-reg ratio in the clinics.
Das S et al. · Critical reviews in microbiology (2023)
Furthermore, it discusses future trends for formulating more effective population-specific probiotics and implications of paraprobiotics and postbiotics as effective therapeutics.
Recent developments in probiotics used against vaginal microbiome dysbiosis have shown great promise in restoring the normal microbiota including preventing the loss of beneficial bacteria.
However, further in-depth studies are warranted to ensure long-term protection by probiotics.
This review highlights various aspects of the vaginal microenvironment in different phases of growth and diverse ethnicities.
Cooper TE et al. · The Cochrane database of systematic reviews (2023)
We found very few studies that adequately test biotic supplementation as alternative treatments for improving kidney function, GI symptoms, dialysis outcomes, allograft function, patient-reported outcomes, CVD, cancer, reducing uraemic toxins, and adverse effects.
MD -0.64 [-9.51, 8.23]OR 12 [0.65, 2.2]↑95 %
Compared to certain strains of probiotics, it is uncertain whether a different strain of probiotic improves eGFR at eight weeks (1 study, 30 participants: MD -0.64 mL/min, 95% CI -9.51 to 8.23; very low certainty evidence).
Compared to placebo or no treatment, it is uncertain whether synbiotics improve eGFR at six or 12 weeks (2 studies, 98 participants: MD 1.42 mL/min, 95% CI 0.65 to 2.2) or change in any GI upset or intolerance at 12 weeks because the certainty of the evidence was very low.
Compared to placebo or no treatment, it is uncertain whether prebiotics improves indoxyl sulfate at eight weeks (2 studies, 75 participants: SMD -0.14 mg/L, 95% CI -0.60 to 0.31; very low certainty evidence) or microbiota composition because the certainty of the evidence is very low.
Macrea C et al. · Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia (2023)
Some unmet needs in this field include determination of the dominant type of microbiota in specific patients with depression; study of microbiome-directed/driven treatment regarding dose and duration adjustments; and multiple versus single strain treatments.
Probiotic/prebiotic/postbiotic treatments were proven to be safe, with few and mild side effects.
Probiotics seemingly could be beneficial in patients with depression, as evidenced by well-established depression scales.
Based on this finding and the high tolerability and safety of probiotics, no caveats against their routine use can be made.
Stramazzo I et al. · Advances in experimental medicine and biology (2023)
The overall results of the present review article strengthen the existence of a bidirectional relationship between the intestine, with its microbial set, and thyroid homeostasis, thus supporting the newly recognized entity known as the gut-thyroid axis.
Lastly, some studies described the use of probiotics or symbiotic supplementation aimed at modulating gut microbiota composition for therapeutic purposes.
The overall results of the present review article strengthen the existence of a bidirectional relationship between the intestine, with its microbial set, and thyroid homeostasis, thus supporting the newly recognized entity known as the gut-thyroid axis.
The majority of the articles report the effects of direct ingestion of different '-biotics' without blending in any food product.
Postbiotic components exhibit properties of pro and anti-immune, anti-tumor, anti-microbial, antioxidant, and anti-biofilm.
More research is required on the efficient conversion of probiotics to paraprobiotics, the isolation and purification of different postbiotics, and stability studies during the shelf life.
The majority of the articles report the effects of direct ingestion of different '-biotics' without blending in any food product.
He J et al. · Critical reviews in food science and nutrition (2023)
This review will promote the further development of probiotic dairy products, provide directions for the research and development of probiotic-related products, and help guide the general public to choose and purchase probiotic fermentation products.
This proposal aims to analyze the effect of probiotics on the quality characteristics of dairy products, clarify a series of physiological functions of probiotic dairy products and critically evaluate the effectiveness and safety of probiotic dairy products.
Also, dairy products containing inactivated microorganisms were compared with probiotic products.
The addition of probiotics enables dairy products to obtain unique quality characteristics, and probiotic dairy products have better health-promoting effects.
Guo N et al. · Immunity, inflammation and disease (2023)
Probiotics demonstrate significant potential in modulating the immune reactions in UC.
Probiotics demonstrate significant potential in modulating the immune reactions in UC.
Their capacity to modulate different immune cells and inflammation-related processes makes them a promising therapeutic approach for managing UC.
However, further studies are warranted to optimize their use and fully elucidate the molecular mechanisms underlying their beneficial effects in UC treatment.
Duque-Buitrago LF et al. · Critical reviews in food science and nutrition (2023)
The existing literature presents a high risk of bias, and results of the same should be evaluated and replicated with precaution; more rigorous clinical studies are lacking.
Two investigators independently selected and reviewed the titles and abstracts of articles and extracted the study characteristics (PICO framework) and key findings.
Dual quality assessment and data extraction were performed.
We found 28 clinical studies evaluating garlic, turmeric, red peppers, broccoli sprouts, cranberry juice, honey, oils, and probiotics contained in different foods, such as juices, yogurt, and cheese.
This review discussed the active principles and potency of probiotics as evidenced by the known effects on host health, in addition to providing information on the mechanism of action.
Emerging evidence suggests that intestinal bowel diseases can be fatal, but regular probiotic consumption can alleviate disease symptoms.
The use and detailed description of the health benefits of probiotics to consumers in terms of reducing intestinal infection, inflammation, and digestive disorders are discussed in this review.
The well-designed and controlled studies that examined the use of probiotics to reduce life-threatening activities caused by intestinal bowel diseases are also covered.