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Head-to-head evidence comparison — which supplement is right for you?
Aged Garlic Extract wins 2 of 3 categories. Both are solid choices — the best pick depends on your specific goals.
Verdict
Likely helps
13 of 14 studies with measurable effects showed benefit.
Top outcomes
Verdict
Likely helps
4 of 4 studies with measurable effects showed benefit.
Top outcomes
Shared outcomes (1)
Outcomes where both Aged Garlic Extract and Dong Quai have evidence — compare verdict strength side-by-side.
600-1200mg aged garlic extract
With meals, Split into 2 doses
Kyolic Aged Garlic Extract (most studied)
500-1500mg dried root extract daily
Divided doses with meals, Traditional use often stops during menstruation
Standardized extract
8-12 weeks
12+ weeks
4-8 weeks
2-3 cycles
2-3 cycles
4-8 weeks
Ongoing
Effects of aged garlic extract on blood pressure in hypertensive patients: A systematic review and meta-analysis of randomized controlled trials
Prostaglandins & other lipid mediators (2024) · Meta analysis · n=584
AGE tea supplementation reduces systolic blood pressure (SBP) (WMD: -4.03; %95CI: -6.87, -1.20; I2: 57.1 %) and diastolic blood pressure (DBP) (WMD: -1.44; 95 % CI= -2.87, -0.02; P = 0.052; I2: 36.8 %; P: 0.105).
Effect of garlic extract on markers of lipid metabolism and inflammation in coronary artery disease (CAD) patients: A systematic review and meta-analysis
Phytotherapy research : PTR (2023) · Meta analysis
The standardized mean difference with 95% CI was calculated using fixed-effect or random-effect models.
A meta-analysis of randomized, double-blind, placebo-controlled trials for the effects of garlic on serum lipid profiles
Journal of the science of food and agriculture (2012) · Meta analysis · n=26
Compared with the placebo groups, serum TC and TG levels in the garlic group were reduced by 0.28 (95% CI, -0.45, -0.11) mmol L⁻¹ (P = 0.001) and 0.13 (95% CI, -0.20, -0.06) mmol L⁻¹ (P < 0.001), respectively.
Treatment of chronic urticaria with traditional Chinese medicine: A systematic review, meta-analysis, and medication regularity
Medicine (2025) · Meta analysis · n=1192
TCM has great advantages in the treatment of CU, can effectively improve the symptoms, the curative effect is stable and safe, but there are still some deficiencies in the standardization of curative effect evaluation.
A review of traditional Chinese medicine for treatment of glioblastoma
Bioscience trends (2020) · Systematic review
Although the current treatment is multimodal, including surgical resection, radiotherapy, and chemotherapy, it does not significantly improve survival time.
Z-ligustilide: A review of its pharmacokinetics and pharmacology
Phytotherapy research : PTR (2020) · Systematic review
New evidence suggests that Z-ligustilide has a wide range of pharmacological properties, including anticancer, antiinflammatory, anti-oxidant as well as neuroprotective activities and so on.
Meta-analysis shows modest SBP reduction of ~4 mmHg and DBP reduction of ~1.4 mmHg. Effect size is relatively small compared to pharmaceutical interventions. Studies primarily used aged garlic extract forms.
Evidence limited to one small RCT (n=120) in cervical spondylosis patients using combination therapy. Effects on menstrual regulation are largely traditional use claims without direct study validation. Meta-analysis on amenorrhea treatment showed 91% effectiveness but used combination TCM formulas, not isolated dong quai.
AI-estimated from published studies. Interpret as directional guidance.
Aged Garlic Extract has a higher evidence score (9/10 vs 8.5/10) and wins in 2 of 3 categories.
For reduce inflammation, Aged Garlic Extract has a higher relevance score (90 vs 55).
No known interactions between Aged Garlic Extract and Dong Quai have been documented in our database. However, always consult a healthcare provider before combining supplements.