We use essential cookies (authentication, your saved goals/stack) by default. With your permission we'll also enable privacy-respecting analytics (Vercel Web Analytics, anonymous load-time metrics) and error-replay diagnostics (Sentry — DOM snapshots only when an error fires) so we can fix bugs faster. Learn more
Dong Quai (Angelica sinensis)
Promotes blood circulation and menstrual regularity — a cornerstone of Chinese medicine for women's health for 2,000+ years.
What the evidence says
Dong Quai appears to help in 4 of 4 studies with measurable effects — the evidence leans clearly favourable.
Most evidence is from high-quality meta-analyses and randomised trials published 2005–2026 with a typical study size of 50 participants.
Based on 34 studies · 2 meta-analyses · 13 RCTs · 5,698 total participants
Confidence
HighWhat the studies found
By outcome
Dong Quai has an evidence score of 8.5/10 — very strong evidence based on 34 indexed studies, including 3 meta-analyses. Promotes blood circulation and menstrual regularity — a cornerstone of Chinese medicine for women's health for 2,000+ years.
The commonly studied dose of Dong Quai is 500-1500mg dried root extract daily. Research points to an estimated optimal dose around 1500mg, with a minimum effective dose near 500mg. Individual response varies — start low and adjust.
The best time to take Dong Quai is with meals. Taking it with food is preferred. Dong quai (Angelica sinensis) contains lipophilic phthalides and ferulic acid that benefit from food-assisted absorption.
Last reviewed May 2026 · evidence from 39 studies · how we score
This information is for educational purposes only. It is not a substitute for professional medical advice. Always consult a qualified healthcare provider before starting, stopping, or changing any supplement or medication.
Dong Quai (Angelica sinensis) has been a cornerstone of Traditional Chinese Medicine for over 2,000 years, primarily for women's health concerns. Often called 'female ginseng,' it's traditionally used to support menstrual regularity, relieve menstrual discomfort, and promote blood circulation. While Western research is limited, its long history of use and emerging studies support its role in women's health, though more rigorous research is needed.
Promotes blood flow and reduces stagnation
May relax uterine smooth muscle
Weak estrogen-like effects
How Dong Quai works — from molecular targets to health outcomes. Click an edge to see supporting research.This visualization is in beta — pathways are being refined and expanded.
500-1500mg dried root extract daily
Loading: Start with lower dose; traditionally used in combination formulas
Take with food
| Form | Type |
|---|---|
| 💊Standardized extract | Recommended |
| 💊Dried root capsules | Alternative |
| 💧Tincture | Alternative |
| 💊Traditional decoction | Alternative |
Quality varies significantly. Look for standardized extracts or reputable TCM sources.
Minimum: 8 weeks
Optimal: 12 weeks
Cycling: Traditional use often involves cycling with menstrual cycle or taking breaks
Note: In TCM, often used in combination with other herbs rather than alone. Some practitioners recommend stopping during menstruation.
Evidence limited to one small RCT (n=120) in cervical spondylosis patients using combination therapy. Effects on menstrual regulation are largely traditional use claims without direct study validation. Meta-analysis on amenorrhea treatment showed 91% effectiveness but used combination TCM formulas, not isolated dong quai.
Reduced menstrual cramps and discomfort
More regular menstrual cycles
Better peripheral blood flow
May increase menstrual flow or bleeding risk
Avoid — Uterine stimulant properties can induce contractions and miscarriage
Avoid; insufficient safety data
May significantly increase bleeding risk
May have additive hormonal effects
May enhance blood pressure lowering
Tip: Reduce dose or stop during menstruation
Tip: Use sun protection
Tip: Take with food
Dong Quai is generally safe at recommended doses, with a few precautions worth noting. The most commonly reported side effects are increased menstrual flow, photosensitivity, GI upset. Use caution if any of these apply to you: Pregnancy (may stimulate uterus); Heavy menstrual bleeding; Hormone-sensitive cancers.
Soy Isoflavones
Likely helpsPlant compounds with weak estrogenic effects that support menopausal symptoms, bone health, and cardiovascular function.
Tap node to isolate • Pinch to zoom • Tap edge for research