Loading…
We use essential cookies (authentication, your saved goals/stack) by default. With your permission we’ll also enable privacy-respecting analytics (Vercel Web Analytics, anonymous load-time metrics) and error-replay diagnostics (Sentry — DOM snapshots only when an error fires) so we can fix bugs faster. Learn more about cookies
Head-to-head evidence comparison — which supplement is right for you?
Bergamot vs CoQ10: CoQ10 has the stronger overall evidence (8 vs 6.5/10); they're alternatives for support heart health — the best pick depends on your goals. Take the 60-second quiz for a pick tailored to your goals.
CoQ10 wins 2 of 3 categories. Both are solid choices — the best pick depends on your specific goals.
Verdict
Too few graded studies
0 of 1 studies with measurable effects showed benefit.
Top outcomes
Verdict
Likely helps
9 of 10 studies with measurable effects showed benefit.
Top outcomes
500-1000mg bergamot polyphenolic fraction (BPF)
With meals, Once or twice daily
Bergamot polyphenolic fraction (BPF) — Bergamonte is well-studied
100-300mg daily
With fatty meal
Ubiquinol (reduced form)
4-12 weeks
4-12 weeks
8-12 weeks
4-12 weeks
8-12 weeks
4-8 weeks
2-8 weeks
A network meta-analysis on the comparative effect of nutraceuticals on lipid profile in adults
Pharmacological research (2022) · Meta analysis · n=13062
Evidence for bergamot effect was based on relatively small study group and may require further investigations.
Randomized, Double-Blind, Placebo-Controlled Trial to Test the Effects of a Nutraceutical Combination Monacolin K-Free on the Lipid and Inflammatory Profile of Subjects with Hypercholesterolemia
Nutrients (2022) · Rct · n=118
Compared to the placebo, at 6 and 12 weeks, NC did not significantly reduce total cholesterol (p = 0.083), LDL cholesterol (p = 0.150), and triglycerides (p = 0.822).
Effect of bergamot on lipid profile in humans: A systematic review
Critical reviews in food science and nutrition (2020) · Systematic review
Although statins can reduce LDLc by 50-60%, less than 20% of patients with high risk of CVD achieve LDL targets.
Efficacy and Safety of Coenzyme Q10 Supplementation in the Treatment of Polycystic Ovary Syndrome: a Systematic Review and Meta-analysis
Reproductive sciences (Thousand Oaks, Calif.) (2023) · Meta analysis · n=1021
Meta-analysis of 9 randomised trials with 1,021 women with polycystic ovary syndrome.
Coenzyme Q10 for heart failure
The Cochrane database of systematic reviews (2021) · Meta analysis · n=1573
Coenzyme Q10 probably reduces the risk of all-cause mortality more than control (RR 0.58, 95% CI 0.35 to 0.95; 1 study, 420 participants; number needed to treat for an additional beneficial outcome (NNTB) 13.3; moderate-quality evidence).
Antioxidants for female subfertility
The Cochrane database of systematic reviews (2017) · Meta analysis · n=6510
This suggests that among subfertile women with an expected clinical pregnancy rate of 22%, the rate among women using antioxidants would be between 27% and 33%.
CoQ10 has a higher evidence score (8/10 vs 6.5/10) and wins in 2 of 3 categories.
For support heart health, Bergamot has a higher relevance score (90 vs 80).
No documented interaction was found in the data searched. This does not establish that this exact combination is safe.
What genuinely lowers LDL/triglycerides — and why "red yeast rice" is a statin in disguise.
The honest tier list — proven staples vs situational vs mostly marketing. The hub the other guides feed into.
Tired? Why most "energy" pills only work if they fix a deficit — and how to find yours first.
Magnesium, riboflavin, CoQ10 — the supplements with real migraine-prevention evidence (and doses).
The right pick depends on your goals. Answer a few quick questions for a personalised recommendation — or dig into the full evidence on each.