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Head-to-head evidence comparison — which supplement is right for you?
Bergamot vs Magnesium: Magnesium has the stronger overall evidence (8.5 vs 6.5/10); they're alternatives for support heart health — the best pick depends on your goals. Take the 60-second quiz for a pick tailored to your goals.
Magnesium wins 2 of 3 categories. Both are solid choices — the best pick depends on your specific goals.
Verdict
Too few graded studies
0 of 1 studies with measurable effects showed benefit.
Top outcomes
Verdict
Mixed evidence
2 of 6 studies with measurable effects showed benefit.
Top outcomes
500-1000mg bergamot polyphenolic fraction (BPF)
With meals, Once or twice daily
Bergamot polyphenolic fraction (BPF) — Bergamonte is well-studied
200-250mg elemental magnesium daily
Evening for sleep/relaxation (glycinate), Morning for energy (malate), Anytime (citrate)
Depends on goal - see notes
and 4 more not shown
4-12 weeks
4-12 weeks
8-12 weeks
1-2 weeks
1-2 weeks
1 week
Immediate
A network meta-analysis on the comparative effect of nutraceuticals on lipid profile in adults
Pharmacological research (2022) · Meta analysis · n=13062
Evidence for bergamot effect was based on relatively small study group and may require further investigations.
Randomized, Double-Blind, Placebo-Controlled Trial to Test the Effects of a Nutraceutical Combination Monacolin K-Free on the Lipid and Inflammatory Profile of Subjects with Hypercholesterolemia
Nutrients (2022) · Rct · n=118
Compared to the placebo, at 6 and 12 weeks, NC did not significantly reduce total cholesterol (p = 0.083), LDL cholesterol (p = 0.150), and triglycerides (p = 0.822).
Effect of bergamot on lipid profile in humans: A systematic review
Critical reviews in food science and nutrition (2020) · Systematic review
Although statins can reduce LDLc by 50-60%, less than 20% of patients with high risk of CVD achieve LDL targets.
Magnesium supplementation in pregnancy
The Cochrane database of systematic reviews (2014) · Meta analysis · n=9090
Ten trials involving 9090 women and their babies. Only two were judged to be of high quality overall.
Magnesium Supplementation and Blood Pressure: A Systematic Review and Meta-Analysis
Hypertension (2025) · Meta analysis · n=2709
38 RCTs with 2709 participants, median 365 mg elemental magnesium for a median 12 weeks. Systolic BP -2.81 mmHg (95% CI -4.32 to -1.29), diastolic -2.05 mmHg versus placebo.
Magnesium and Potassium Supplementation for Systolic Blood Pressure Reduction in the General Normotensive Population: A Systematic Review and Subgroup Meta-Analysis for Optimal Dosage and Treatment Length
Nutrients (2024) · Meta analysis
Both supplements demonstrated greater reductions in SBP for the general population at lower dosages and longer treatment durations.
Magnesium has a higher evidence score (8.5/10 vs 6.5/10) and wins in 2 of 3 categories.
For support heart health, Bergamot has a higher relevance score (90 vs 75).
No documented interaction was found in the data searched. This does not establish that this exact combination is safe.
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The right pick depends on your goals. Answer a few quick questions for a personalised recommendation — or dig into the full evidence on each.