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Head-to-head evidence comparison — which supplement is right for you?
CoQ10 vs Pterostilbene: CoQ10 has the stronger overall evidence (8 vs 4/10); they're alternatives for support heart health — the best pick depends on your goals. Take the 60-second quiz for a pick tailored to your goals.
CoQ10 wins 2 of 3 categories. Both are solid choices — the best pick depends on your specific goals.
Verdict
Likely helps
9 of 10 studies with measurable effects showed benefit.
Top outcomes
Verdict
Mostly mechanism / observational
Top outcomes
Shared outcomes (1)
Outcomes where both CoQ10 and Pterostilbene have evidence — compare verdict strength side-by-side.
100-300mg daily
With fatty meal
Ubiquinol (reduced form)
50-100mg daily
Morning with breakfast, Can be divided into two doses
Pterostilbene capsules
4-12 weeks
8-12 weeks
4-8 weeks
2-8 weeks
4-8 weeks
6-12 weeks
4-8 weeks
Weeks
Efficacy and Safety of Coenzyme Q10 Supplementation in the Treatment of Polycystic Ovary Syndrome: a Systematic Review and Meta-analysis
Reproductive sciences (Thousand Oaks, Calif.) (2023) · Meta analysis · n=1021
Meta-analysis of 9 randomised trials with 1,021 women with polycystic ovary syndrome.
Coenzyme Q10 for heart failure
The Cochrane database of systematic reviews (2021) · Meta analysis · n=1573
Coenzyme Q10 probably reduces the risk of all-cause mortality more than control (RR 0.58, 95% CI 0.35 to 0.95; 1 study, 420 participants; number needed to treat for an additional beneficial outcome (NNTB) 13.3; moderate-quality evidence).
Antioxidants for female subfertility
The Cochrane database of systematic reviews (2017) · Meta analysis · n=6510
This suggests that among subfertile women with an expected clinical pregnancy rate of 22%, the rate among women using antioxidants would be between 27% and 33%.
Resveratrol and Its Analogues: Anti-ageing Effects and Underlying Mechanisms
Sub-cellular biochemistry (2024) · Review
The anti-ageing mechanisms of resveratrol and its analogues are complex and multifactorial, involving suppressing oxidative stress, ameliorating inflammation, activating SIRT1 pathway, reducing DNA damage, etc.
Antiobesity pathways of pterostilbene and resveratrol: a comprehensive insight
Critical reviews in food science and nutrition (2024) · Review
Stilbenes are products of the plant phenylpropanoid pathway.
Dietary Supplementation With NAD+-Boosting Compounds in Humans: Current Knowledge and Future Directions
The journals of gerontology. Series A, Biological sciences and medical sciences (2023) · Review
Review of chronic oral NAD+ precursor supplementation in humans. Nicotinamide riboside given with pterostilbene was one of the three most studied options.
CoQ10 has a higher evidence score (8/10 vs 4/10) and wins in 2 of 3 categories.
For support heart health, CoQ10 has a higher relevance score (80 vs 52).
No documented interaction was found in the data searched. This does not establish that this exact combination is safe.
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The right pick depends on your goals. Answer a few quick questions for a personalised recommendation — or dig into the full evidence on each.