Loading…
We use essential cookies (authentication, your saved goals/stack) by default. With your permission we’ll also enable privacy-respecting analytics (Vercel Web Analytics, anonymous load-time metrics) and error-replay diagnostics (Sentry — DOM snapshots only when an error fires) so we can fix bugs faster. Learn more about cookies
Head-to-head evidence comparison — which supplement is right for you?
CoQ10 vs Theacrine: CoQ10 has the stronger overall evidence (8 vs 5.5/10); they're alternatives for boost daily energy — the best pick depends on your goals. Take the 60-second quiz for a pick tailored to your goals.
CoQ10 wins 2 of 3 categories. Both are solid choices — the best pick depends on your specific goals.
Verdict
Likely helps
9 of 10 studies with measurable effects showed benefit.
Top outcomes
Verdict
Too few graded studies
Top outcomes
Shared outcomes (1)
Outcomes where both CoQ10 and Theacrine have evidence — compare verdict strength side-by-side.
100-300mg daily
With fatty meal
Ubiquinol (reduced form)
100-200mg daily
Morning or early afternoon, 30-60 minutes before focus work, Pre-workout
TeaCrine (branded theacrine)
4-12 weeks
8-12 weeks
4-8 weeks
2-8 weeks
30-60 minutes, lasts 4-6 hours
30-60 minutes
30-60 minutes
30-60 minutes
Efficacy and Safety of Coenzyme Q10 Supplementation in the Treatment of Polycystic Ovary Syndrome: a Systematic Review and Meta-analysis
Reproductive sciences (Thousand Oaks, Calif.) (2023) · Meta analysis · n=1021
Meta-analysis of 9 randomised trials with 1,021 women with polycystic ovary syndrome.
Coenzyme Q10 for heart failure
The Cochrane database of systematic reviews (2021) · Meta analysis · n=1573
Coenzyme Q10 probably reduces the risk of all-cause mortality more than control (RR 0.58, 95% CI 0.35 to 0.95; 1 study, 420 participants; number needed to treat for an additional beneficial outcome (NNTB) 13.3; moderate-quality evidence).
Antioxidants for female subfertility
The Cochrane database of systematic reviews (2017) · Meta analysis · n=6510
This suggests that among subfertile women with an expected clinical pregnancy rate of 22%, the rate among women using antioxidants would be between 27% and 33%.
A caffeine and theacrine combination improves cognitive performance in tactical personnel under physically fatiguing conditions
Journal of the International Society of Sports Nutrition (2025) · Rct · n=20
In the Object Hit & Avoid task, CAF and CTC significantly improved task accuracy (p < 0.01) while reducing omission (p < 0.01) and commission errors (p < 0.01) compared to PLA.
Theacrine as a novel ergogenic aid: impact on canoe sprint performance
Journal of the International Society of Sports Nutrition (2025) · Rct · n=20
Twenty highly trained male canoe sprint athletes completed a randomised crossover of placebo, caffeine, theacrine, and caffeine plus theacrine.
Uncovering the effects and mechanisms of tea and its components on depression, anxiety, and sleep disorders: A comprehensive review
Food research international (Ottawa, Ont.) (2024) · Review
A narrative overview of animal, clinical, and epidemiological studies on tea and its components, not a systematic review with pooled results.
CoQ10 has a higher evidence score (8/10 vs 5.5/10) and wins in 2 of 3 categories.
For boost daily energy, CoQ10 has a higher relevance score (75 vs 35).
No documented interaction was found in the data searched. This does not establish that this exact combination is safe.
The honest tier list — proven staples vs situational vs mostly marketing. The hub the other guides feed into.
Tired? Why most "energy" pills only work if they fix a deficit — and how to find yours first.
Magnesium, riboflavin, CoQ10 — the supplements with real migraine-prevention evidence (and doses).
CoQ10, zinc, selenium, carnitine modestly help sperm parameters — but live-birth evidence is weak.
The right pick depends on your goals. Answer a few quick questions for a personalised recommendation — or dig into the full evidence on each.