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Head-to-head evidence comparison — which supplement is right for you?
Inositol wins 2 of 3 categories. Both are solid choices — the best pick depends on your specific goals.
Verdict
Probably helps
14 of 21 studies with measurable effects showed benefit.
Top outcomes
Verdict
Likely helps
4 of 5 studies with measurable effects showed benefit.
Top outcomes
2-4g for general anxiety; 12-18g for OCD/panic
Divided into 2-3 doses, With or without food
Myo-inositol powder (most economical for higher doses)
100-200mg
Morning with coffee for focus, Evening for relaxation, As needed for stress
Suntheanine® capsules or powder
4-6 weeks
6-12 weeks
3-6 months
First 1-2 weeks
30-60 minutes
30-60 minutes
30-60 minutes
Varies
Antenatal dietary supplementation with myo-inositol for preventing gestational diabetes
The Cochrane database of systematic reviews (2023) · Meta analysis · n=1319
For the primary neonatal outcomes, only one study measured the risk of a large-for-gestational-age infant and found myo-inositol was associated with both appreciable benefit and harm (RR 1.40, 95% CI 0.65 to 3.02; 1 study, 234 infants; low-certainty evidence).
Inositol Nutritional Supplementation for the Prevention of Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Nutrients (2022) · Meta analysis · n=1321
Pooled results were expressed as relative risk (RR) or mean difference (MD) with a 95% confidence interval (95% CI).
Antioxidants for female subfertility
The Cochrane database of systematic reviews (2020) · Meta analysis · n=7760
Due to the very low-quality of the evidence we are uncertain whether antioxidants improve live birth rate compared with placebo or no treatment/standard treatment (odds ratio (OR) 1.81, 95% confidence interval (CI) 1.36 to 2.43; P < 0.001, I2 = 29%; 13 RCTs, 1227 women).
The effects of L-theanine consumption on sleep outcomes: A systematic review and meta-analysis
Sleep medicine reviews (2025) · Meta analysis · n=897
The findings indicate the potential use of L-theanine in the management of sleep disturbances; however, the lack of studies on "pure" L-theanine warrants further investigation.
Efficiency of Different Supplements in Alleviating Symptoms of ADHD with or Without the Use of Stimulants: A Systematic Review
Nutrients (2025) · Systematic review
The evidence revealed the potential use of supplements as complementary ADHD treatments under clinical guidance.
Analysis of the Effects of Known Sleep-Support Supplements in Relation to Life Habits, Sleep Conditions, and Sleep Problems
Nutrients (2023) · Rct · n=160
All the tested supplements were found to ameliorate sleep problems significantly (Analysis 1).
Based on multiple meta-analyses showing inositol benefits for PCOS including improved menstrual regularity, hormonal parameters, and metabolic markers. Evidence quality varies across studies with some limitations noted in systematic reviews.
Meta-analysis (n=897) and multiple RCTs support sleep benefits. Studies often used L-theanine in combination with other compounds, limiting pure L-theanine effect attribution. Effects include reduced sleep onset latency and improved subjective sleep quality.
AI-estimated from published studies. Interpret as directional guidance.
Inositol has a higher evidence score (7/10 vs 6/10) and wins in 2 of 3 categories.
Both Inositol and L-Theanine score equally (85) for reduce anxiety & stress.
No known interactions between Inositol and L-Theanine have been documented in our database. However, always consult a healthcare provider before combining supplements.