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Head-to-head evidence comparison — which supplement is right for you?
Maca vs Tribulus: they're closely matched on evidence (5.5 vs 5.5/10); they're alternatives for menopause support — the best pick depends on your goals. Take the 60-second quiz for a pick tailored to your goals.
Maca and Tribulus are closely matched across evidence, studies, and safety.
Verdict
Likely helps
3 of 3 studies with measurable effects showed benefit.
Top outcomes
Verdict
Likely helps
4 of 4 studies with measurable effects showed benefit.
Top outcomes
Shared outcomes (2)
Outcomes where both Maca and Tribulus have evidence — compare verdict strength side-by-side.
1500-3000mg
Morning or early afternoon, With food
Gelatinized maca powder (easier to digest)
250-750mg daily (standardized to 45-60% saponins)
With meals, Morning or divided doses
Extract standardized to 45-60% saponins (protodioscin)
6-12 weeks
4-8 weeks
4-8 weeks
2-4 weeks
4-8 weeks
N/A
Effects of Maca (Lepidium meyenii Walp.) on Physical Performance in Animals and Humans: A Systematic Review and Meta-Analysis
Nutrients (2024) · Meta analysis
They revealed a large effect for all outcomes (SMD: FST = 2.26, RRT = 6.26, GST = 5.23, LA = -1.01, and BLA = -1.70).
A review of the study of active components and their pharmacology value in Lepidium meyenii (Maca)
Phytotherapy research : PTR (2021) · Systematic review
Additionally, the research on the change of active components in Maca at different growth stages by MS will be beneficial to full utilization of active components in Maca and other natural resources.
Enhancement of Interferon-γ Secretion by Lepidium meyenii Extract Supplementation After Exhaustive Endurance Exercise in Healthy Men: A Double-blind, Placebo-controlled Trial
International journal of medical sciences (2025) · Rct · n=20
Regarding the main time effect, the number of lymphocytes in all participants was significantly lower at 2 and 4 hours after exercise than before supplementation.
Effects of Tribulus (Tribulus terrestris L.) Supplementation on Erectile Dysfunction and Testosterone Levels in Men-A Systematic Review of Clinical Trials
Nutrients (2025) · Systematic review · n=172
The Jadad score revealed low methodological quality for 50% of the studies.
Dietary Supplements for Erectile Dysfunction: Analysis of Marketed Products, Systematic Review, Meta-Analysis and Rational Use
Nutrients (2023) · Meta analysis
Based on the scoring system, 2 (8%) supplements matched with the cluster of higher expected efficacy, 3 (12%) with the lower efficacy cluster and 20 (80%) matched with the criterion of no expected efficacy.
Beneficial effects of natural products on female sexual dysfunction: A systematic review and meta-analysis
Phytomedicine : international journal of phytotherapy and phytopharmacology (2021) · Meta analysis · n=536
Tribulus terrestris showed a significant positive effect in improving overall female sexual function (SMD = 1.12, 95% CI = 0.46 - 1.79, p = 0.001) compared to placebo.
Based on meta-analysis showing large effect sizes for physical performance outcomes. Effects may vary significantly between raw and gelatinized forms. Limited human studies with small sample sizes.
Based on systematic review showing improvement in 3 of 5 studies at 400-750mg doses. Studies had low methodological quality (50% low Jadad scores). Effects primarily in men with existing ED.
AI-estimated from published studies. Interpret as directional guidance.
Both Maca and Tribulus are closely matched — the best choice depends on your specific health goals.
For menopause support, Maca has a higher relevance score (85 vs 72).
No known interactions between Maca and Tribulus have been documented in our database. However, always consult a healthcare provider before combining supplements.
CoQ10, zinc, selenium, carnitine modestly help sperm parameters — but live-birth evidence is weak.
Hot flashes, bone, sleep, muscle — the basics that hold up vs the phytoestrogen hype.
The transition years (40s): cycle changes, mood, sleep, brain fog — foundations, vitex, and starting muscle work early.
Mostly hype unless you’re deficient — what has modest evidence vs what doesn’t, and when to see a doctor.
The right pick depends on your goals. Answer a few quick questions for a personalised recommendation — or dig into the full evidence on each.