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Head-to-head evidence comparison — which supplement is right for you?
UC-II wins 1 of 3 categories. Both are solid choices — the best pick depends on your specific goals.
Verdict
Mostly mechanism / observational
Top outcomes
Verdict
Mostly mechanism / observational
Top outcomes
Shared outcomes (1)
Outcomes where both Rosehip and UC-II have evidence — compare verdict strength side-by-side.
5g daily of standardized rosehip powder (the dose used in the OA trials)
with-meals
Standardized rosehip powder (GOPO-standardized)
40mg UC-II daily (providing ~10mg undenatured type II collagen)
any
Undenatured type II collagen (UC-II, 40mg)
3 weeks to 3 months
3-12 weeks
Throughout use
8-24 weeks
8-16 weeks
Throughout use
Does the hip powder of Rosa canina (rosehip) reduce pain in osteoarthritis patients?--a meta-analysis of randomized controlled trials.
Osteoarthritis Cartilage (2008) · Meta analysis · n=287
Pooled three RCTs (287 patients, median 3-month duration)
A powder made from seeds and shells of a rose-hip subspecies (Rosa canina) reduces symptoms of knee and hip osteoarthritis: a randomized, double-blind, placebo-controlled clinical trial.
Scand J Rheumatol (2005) · Crossover · n=94
94 patients, randomized double-blind placebo-controlled crossover, 5g/day for 3 months
The clinical effectiveness of rosehip powder in patients with osteoarthritis. A systematic review.
MMW Fortschr Med (2007) · Systematic review
Systematic review of two double-blind RCTs (N=100 and 112, Jadad score 5)
Efficacy and tolerability of an undenatured type II collagen supplement in modulating knee osteoarthritis symptoms: a multicenter randomized, double-blind, placebo-controlled study.
Nutr J (2016) · Rct · n=191
UC-II 40mg/day improved total WOMAC vs placebo over 180 days
Safety and efficacy of undenatured type II collagen in the treatment of osteoarthritis of the knee: a clinical trial.
Int J Med Sci (2009) · Rct · n=52
UC-II reduced WOMAC 33% vs 14% for glucosamine+chondroitin
Undenatured type II collagen (UC-II(R)) for joint support: a randomized, double-blind, placebo-controlled study in healthy volunteers.
J Int Soc Sports Nutr (2013) · Rct · n=55
Improved average knee extension range vs placebo
UC-II has a higher evidence score (5/10 vs 5/10) and wins in 1 of 3 categories.
For joint health & mobility, UC-II has a higher relevance score (65 vs 62).
No known interactions between Rosehip and UC-II have been documented in our database. However, always consult a healthcare provider before combining supplements.