Kayla Barnes — female-longevity stack

A female-longevity biohacker’s protocol — she reports ~30–35 supplements a day, amended off testing — built on omega-3, vitamin D3+K2, creatine, colostrum and NAD precursors, with hormone-support extras. The publicly named items are below. COI: she has brand partnerships / affiliate relationships. Documented as reported, not endorsed.

Kayla Barnes-Lentz is a longevity-focused entrepreneur and biohacker who runs a women’s-longevity clinic and program and publicly documents her daily optimization protocol.

Website ↗

Documented, not endorsed. What Kayla Barnes-Lentz reports taking (as of 2026-06) — not medical advice, not a recommendation. We sell nothing; each item links to its independently evidence-graded card.

At a glance

Aimed at (inferred from 13 mapped members)

🧬 Longevity & healthspan 7🩺 General health 4😌 Mood & stress 4💪 Performance & recovery 4🧠 Cognition 2

Evidence makeup

2 Strong 8 Moderate 3 Emerging

The stack · 15 compounds

Core

🐟 Cod Liver Oil
Omega-3 EPA/DHA foundation.
Emerging 4.0~1,100 mg omega-3 (Carlson)
☀️ Vitamin D3
Bone, immune and hormone support.
Moderate 7.55,000 IU (with K2)
🦴 Vitamin K2
Directs calcium to bone; paired with D3.
Moderate 6.0no dose info
⚡ Creatine
Muscle and cognition.
Strong 9.55 g · in protein coffee
🥛 Colostrum
Gut and immune support.
Moderate 5.54 scoops
💊 Multivitamin
Broad micronutrient base.
Moderate 6.0no dose info
⏳ NMN
NAD+ precursor.
Moderate 5.5no dose info
🛡️ Glutathione
Master antioxidant.
Emerging 4.8no dose info (Cymbiotika)
✨ Collagen
Skin, hair and nails.
Moderate 6.0no dose info
AG1 (greens powder)not yet mapped
“Nutritional insurance” greens blend (no single SupStack card).
no dose info

Situational

✨ Magnesium
Sleep, stress and hormone support.
Strong 8.5no dose info (glycinate)
😌 Inositol
Hormone / metabolic support.
Moderate 7.0no dose info
🛡️ NAC
Glutathione precursor; hormone support.
Moderate 6.0no dose info
🍅 Lycopene
Antioxidant.
Emerging 4.520 mg
NOVOS Corenot yet mapped
Multi-ingredient longevity blend (no single SupStack card).
no dose info

Not yet mapped: AG1 (greens powder), NOVOS Core.

“no dose info” = publicly known to take it, but no reliable dose has been stated.

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Watch-outs (1)

Multivitamin ✕ Vitamin D3 — Combined D3 intake above 4000 IU/day long-term increases risk of hypercalcemia, hypercalciuria, kidney stone formation, and vascular calcification. The effect is amplified when calcium intake is also high. Quantify total vitamin D from all supplements. If using standalone D3, choose a product accounting for multivitamin D3 content. Monitor serum 25(OH)D; maintain 40–60 ng/mL as optimal range. Avoid exceeding 4000 IU/day without medical supervision and confirmed 25(OH)D testing.

Synergies (4)

Vitamin D3 + Vitamin K2 — K2 prevents arterial calcification while enhancing bone mineralization from vitamin D
Vitamin D3 + Magnesium — Magnesium deficiency impairs vitamin D metabolism and effectiveness
Multivitamin + Vitamin K2 — Complementary coverage of vitamin K-dependent proteins across hepatic (clotting) and extrahepatic (bone, vascular) compartments. Enhanced bone mineral density and reduced vascular calcification compared to either alone.
Multivitamin + Magnesium — Magnesium supplementation enhances the functional efficacy of vitamin D3 and B-vitamins in the multivitamin by providing the essential mineral cofactor for their enzymatic activation and utilization. Improved energy metabolism, sleep, and muscle function outcomes.

Documented supplement–supplement interactions between members of this stack — not a personal interaction check. Full interaction checker →

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Sources: kaylabarnes.com — Female Longevity Protocol · Interview — “I take 35 supplements a day”