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Fadogia Agrestis
Nigerian shrub with preliminary evidence for testosterone and libido support — popular but human research is still very limited.
What the evidence says
Most Fadogia Agrestis studies are mechanism or observational rather than RCTs that measure a clinical effect — keep findings provisional.
Most evidence is from mixed-quality studies published 2005–2023.
Based on 3 studies
Confidence
Very lowBy outcome
Fadogia Agrestis has an evidence score of 2.5/10 — emerging evidence based on 3 indexed studies. Nigerian shrub with preliminary evidence for testosterone and libido support — popular but human research is still very limited.
The commonly studied dose of Fadogia Agrestis is 300-600mg extract daily. Research points to an estimated optimal dose around 450mg, with a minimum effective dose near 300mg. Individual response varies — start low and adjust.
The best time to take Fadogia Agrestis is in the morning. Taking it with food is preferred. Fadogia agrestis is used primarily for testosterone support, and morning dosing aligns with the natural diurnal testosterone rhythm.
Last reviewed May 2026 · evidence from 4 studies · how we score
This information is for educational purposes only. It is not a substitute for professional medical advice. Always consult a qualified healthcare provider before starting, stopping, or changing any supplement or medication.
Fadogia Agrestis is a shrub native to Nigeria traditionally used as an aphrodisiac and for treating erectile dysfunction. It has gained significant popularity in the fitness community for potential testosterone-boosting effects. However, research is very limited - primarily animal studies - and there are potential safety concerns that warrant caution.
May increase testosterone in animal studies
Traditional aphrodisiac use
How Fadogia Agrestis works — from molecular targets to health outcomes. Click an edge to see supporting research.This visualization is in beta — pathways are being refined and expanded.
300-600mg extract daily
Loading: Not established; start conservative
Take with food
| Form | Type |
|---|---|
| 💊Standardized extract | Recommended |
| 💊Capsules | Alternative |
Quality varies significantly. Choose reputable sources with third-party testing.
Minimum: 2 weeks
Optimal: 8 weeks
Cycling: Strong recommendation to cycle: 4-6 weeks on, 4 weeks off
Note: Limited dosing guidance. Conservative approach recommended given limited safety data.
Based solely on animal studies with no human clinical trials. Single rat study showed testosterone increase but also testicular toxicity at higher doses. Effects may not translate to humans.
May increase testosterone (animal data only)
Traditional use for sexual function
Animal studies show potential testicular toxicity at high doses
Exercise caution - limited human safety data
May interfere with hormone replacement; consult endocrinologist
May affect hormonal balance; use with caution
May affect blood sugar levels; monitor glucose
Tip: Cycle use; stay within recommended doses
Fadogia Agrestis is generally safe at recommended doses, with a few precautions worth noting. The most commonly reported side effects are potential testicular effects. Use caution if any of these apply to you: Existing testicular issues; Prostate conditions; Those trying to conceive.
Maca
Likely helpsAndean root that boosts energy and libido through hormonal signaling modulation — different colors (red, black, yellow) have distinct effects.
Tap node to isolate • Pinch to zoom • Tap edge for research