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Digestive and systemic enzymes ranked by evidence, with dosing and the goals they support.
Top picks: Digestive Enzymes, Bromelain, and Serrapeptase.
Enzyme blend that supports digestion of proteins, fats, carbohydrates, and fiber, reducing bloating and improving nutrient absorption.
Proteolytic enzyme from pineapple that aids digestion with food or provides systemic anti-inflammatory and recovery benefits on an empty stomach.
Silkworm-derived proteolytic enzyme popular in Europe and Japan for swelling and sinusitis — but human evidence is thin and mixed; a systematic review judged it insufficient to support routine use.
Supplemental bile acids for fat digestion, mainly after gallbladder removal. The honest verdict: the physiology is sound, but direct human evidence is sparse — only a few small studies, no meta-analyses, and most data come from unrelated disease states rather than fat-digestion trials.