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Head-to-head evidence comparison — which supplement is right for you?
Aged Garlic Extract vs Calcium: Calcium has the stronger overall evidence (8 vs 7.5/10); they're alternatives for inflammation-related symptoms — the best pick depends on your goals. Take the 60-second quiz for a pick tailored to your goals.
Calcium wins 2 of 3 categories. Both are solid choices — the best pick depends on your specific goals.
Verdict
Likely helps
12 of 13 studies with measurable effects showed benefit.
Top outcomes
Verdict
Likely helps
13 of 15 studies with measurable effects showed benefit.
Top outcomes
Shared outcomes (1)
Outcomes where both Aged Garlic Extract and Calcium have evidence — compare verdict strength side-by-side.
600-1200mg aged garlic extract
With meals, Split into 2 doses
Kyolic Aged Garlic Extract (most studied)
1000–1200mg daily (split doses)
Split doses with meals, 500mg with breakfast, 500mg with dinner
Calcium Citrate
and 7 more not shown
8-12 weeks
12+ weeks
4-8 weeks
6-24 months
12-36 months
Throughout pregnancy
Within days of starting
Effects of aged garlic extract on blood pressure in hypertensive patients: A systematic review and meta-analysis of randomized controlled trials
RetractedProstaglandins & other lipid mediators (2024) · Meta analysis · n=584
AGE tea supplementation reduces systolic blood pressure (SBP) (WMD: -4.03; %95CI: -6.87, -1.20; I2: 57.1 %) and diastolic blood pressure (DBP) (WMD: -1.44; 95 % CI= -2.87, -0.02; P = 0.052; I2: 36.8 %; P: 0.105).
Effect of garlic extract on markers of lipid metabolism and inflammation in coronary artery disease (CAD) patients: A systematic review and meta-analysis
Phytotherapy research : PTR (2023) · Meta analysis
The standardized mean difference with 95% CI was calculated using fixed-effect or random-effect models.
A meta-analysis of randomized, double-blind, placebo-controlled trials for the effects of garlic on serum lipid profiles
Journal of the science of food and agriculture (2012) · Meta analysis · n=26
Compared with the placebo groups, serum TC and TG levels in the garlic group were reduced by 0.28 (95% CI, -0.45, -0.11) mmol L⁻¹ (P = 0.001) and 0.13 (95% CI, -0.20, -0.06) mmol L⁻¹ (P < 0.001), respectively.
Effects of combined calcium and vitamin D supplementation on osteoporosis in postmenopausal women: a systematic review and meta-analysis of randomized controlled trials.
Food & Function (2020) · Meta analysis · n=12000
Combined calcium and vitamin D significantly improved lumbar spine BMD in postmenopausal women
Association Between Calcium or Vitamin D Supplementation and Fracture Incidence in Community-Dwelling Older Adults: A Systematic Review and Meta-analysis.
JAMA (2017) · Meta analysis · n=51145
33 trials involving 51,145 participants were analyzed
Vitamin D and Calcium for the Prevention of Fracture: A Systematic Review and Meta-analysis.
JAMA Network Open (2019) · Meta analysis · n=51419
Meta-analysis of 11 randomized clinical trials with 51,419 participants
Meta-analysis shows modest SBP reduction of ~4 mmHg and DBP reduction of ~1.4 mmHg. Effect size is relatively small compared to pharmaceutical interventions. Studies primarily used aged garlic extract forms.
Based on meta-analysis of 59 RCTs showing 0.6-1.8% BMD increases. Requires vitamin D co-supplementation for optimal effect. Effectiveness plateaus beyond 1200mg daily.
AI-estimated from published studies. Interpret as directional guidance.
Calcium has a higher evidence score (8/10 vs 7.5/10) and wins in 2 of 3 categories.
For inflammation-related symptoms, Aged Garlic Extract has a higher relevance score (90 vs 35).
No known interactions between Aged Garlic Extract and Calcium have been documented in our database. However, always consult a healthcare provider before combining supplements.
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When to take what, with or without food, and which supplements compete vs pair well.
The right pick depends on your goals. Answer a few quick questions for a personalised recommendation — or dig into the full evidence on each.