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Head-to-head evidence comparison — which supplement is right for you?
Butcher's Broom vs Potassium: Potassium has the stronger overall evidence (8.5 vs 5/10); they're alternatives for inflammation-related symptoms — the best pick depends on your goals. Take the 60-second quiz for a pick tailored to your goals.
Potassium wins 2 of 3 categories. Both are solid choices — the best pick depends on your specific goals.
Verdict
Mostly mechanism / observational
Top outcomes
Verdict
Probably helps
9 of 13 studies with measurable effects showed benefit.
Top outcomes
Shared outcomes (1)
Outcomes where both Butcher's Broom and Potassium have evidence — compare verdict strength side-by-side.
Standardized Ruscus extract providing ~7-11mg ruscogenins daily (combination products: 1-2 capsules of Ruscus+HMC+vitamin C)
with-meals
Ruscogenin-standardized Ruscus extract
99-500mg daily from supplements (food provides more)
With food to reduce GI upset, Spread throughout day, During/after exercise for athletes
Potassium Citrate or Potassium Gluconate
and 10 more not shown
4-12 weeks
4-12 weeks
Throughout use
2-4 weeks
1-2 weeks
Long-term
With excess or kidney issues
Meta-analysis of clinical trials of Cyclo 3 Fort in the treatment of chronic venous insufficiency.
Int Angiol (2003) · Meta analysis
Reduced CVI symptom-severity scores: pain, heaviness, cramps, paraesthesia, oedema severity
Efficacy and safety of a Butcher's broom preparation (Ruscus aculeatus L. extract) compared to placebo in patients suffering from chronic venous insufficiency.
Arzneimittelforschung (2002) · Rct · n=148
Ruscus extract ALONE reduced leg/ankle circumference (edema) vs placebo
Combination of Ruscus aculeatus extract, hesperidin methyl chalcone and ascorbic acid: a comprehensive review of their pharmacological and clinical effects and of the pathophysiology of chronic venous disease.
Int Angiol (2016) · Review
Venoconstrictive effect on veins + action on microcirculation/lymphatics
Effect of changes in potassium intake on blood pressure: a dose–response meta-analysis of randomized clinical trials (2000–2024)
Clinical Kidney Journal (2025) · Meta analysis · n=2500
Dose-response analysis of RCTs from 2000-2024
Magnesium and Potassium Supplementation for Systolic Blood Pressure Reduction in the General Normotensive Population: A Systematic Review and Subgroup Meta-Analysis for Optimal Dosage and Treatment Length
Nutrients (2024) · Meta analysis
Both supplements demonstrated greater reductions in SBP for the general population at lower dosages and longer treatment durations.
Sex-specific associations between sodium and potassium intake and overall and cause-specific mortality: a large prospective U.S. cohort study, systematic review, and updated meta-analysis of cohort studies
BMC medicine (2024) · Meta analysis · n=237036
Potassium has a higher evidence score (8.5/10 vs 5/10) and wins in 2 of 3 categories.
For inflammation-related symptoms, Potassium has a higher relevance score (85 vs 32).
No known interactions between Butcher's Broom and Potassium have been documented in our database. However, always consult a healthcare provider before combining supplements.
The right pick depends on your goals. Answer a few quick questions for a personalised recommendation — or dig into the full evidence on each.