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Head-to-head evidence comparison — which supplement is right for you?
Cat's Claw and Potassium are closely matched across evidence, studies, and safety.
Verdict
Mixed evidence
1 of 3 studies with measurable effects showed benefit.
Top outcomes
Verdict
Probably helps
10 of 15 studies with measurable effects showed benefit.
Top outcomes
Shared outcomes (1)
Outcomes where both Cat's Claw and Potassium have evidence — compare verdict strength side-by-side.
250-350mg standardized extract or 1-3g dried bark, 2-3x daily
With meals
Standardized extract (3% oxindole alkaloids)
99-500mg daily from supplements (food provides more)
With food to reduce GI upset, Spread throughout day, During/after exercise for athletes
Potassium Citrate or Potassium Gluconate
4-8 weeks
2-4 weeks
4-8 weeks
2-4 weeks
1-2 weeks
Long-term
With excess or kidney issues
Uncaria tomentosa as a Promising Natural Source of Molecules with Multiple Activities: Review of Its Ethnomedicinal Uses, Phytochemistry and Pharmacology
International journal of molecular sciences (2025) · Systematic review
The present paper reviews research progress relating to the ethnobotany, phytochemistry and pharmacology of Ut, and some promising research routes are also discussed.
Systemic therapies for preventing or treating aromatase inhibitor-induced musculoskeletal symptoms in early breast cancer
The Cochrane database of systematic reviews (2022) · Meta analysis · n=137
The two studies, investigating vitamin D and omega-3 fatty acids, showed a treatment effect with 95% CIs that did not include an MCID for pain.
Bioactive Molecules from Tropical American Plants: Potential Anti-Inflammatory Agents for Cytokine Storm Management
Molecules (Basel, Switzerland) (2025) · Systematic review
Key polyphenols, like quercetin and luteolin, found in plants such as Achyrocline satureioides and Mangifera indica demonstrate the downregulation of NF-κB and inhibition of pro-inflammatory cytokines.
Effect of changes in potassium intake on blood pressure: a dose–response meta-analysis of randomized clinical trials (2000–2024)
Clinical Kidney Journal (2025) · Meta analysis · n=2500
Dose-response analysis of RCTs from 2000-2024
Magnesium and Potassium Supplementation for Systolic Blood Pressure Reduction in the General Normotensive Population: A Systematic Review and Subgroup Meta-Analysis for Optimal Dosage and Treatment Length
Nutrients (2024) · Meta analysis
Both supplements demonstrated greater reductions in SBP for the general population at lower dosages and longer treatment durations.
Sex-specific associations between sodium and potassium intake and overall and cause-specific mortality: a large prospective U.S. cohort study, systematic review, and updated meta-analysis of cohort studies
BMC medicine (2024) · Meta analysis · n=237036
Meta-analysis examining Potassium efficacy
Based on systematic review evidence showing significant pain reduction in knee osteoarthritis. Limited number of direct RCTs. Most studies used 250-350mg doses. GI upset more common at higher doses.
AI-estimated from published studies. Interpret as directional guidance.
Both Cat's Claw and Potassium are closely matched — the best choice depends on your specific health goals.
For reduce inflammation, Potassium has a higher relevance score (85 vs 75).
No known interactions between Cat's Claw and Potassium have been documented in our database. However, always consult a healthcare provider before combining supplements.