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Head-to-head evidence comparison — which supplement is right for you?
DHEA vs Raspberry Leaf: DHEA has the stronger overall evidence (5.5 vs 4/10); they're alternatives for support mood — the best pick depends on your goals. Take the 60-second quiz for a pick tailored to your goals.
DHEA wins 2 of 3 categories. Both are solid choices — the best pick depends on your specific goals.
Verdict
Probably helps
3 of 5 studies with measurable effects showed benefit.
Top outcomes
Verdict
Mostly mechanism / observational
1 of 2 studies with measurable effects showed benefit.
Top outcomes
Shared outcomes (1)
Outcomes where both DHEA and Raspberry Leaf have evidence — compare verdict strength side-by-side.
25-50mg for women; 50-100mg for men (start low) (the one cited trial used 50 mg a day in women with adrenal insufficiency, no cited trial studied men, and a cited meta-analysis in postmenopausal women with normal adrenal function found no significant benefit)
Morning (mimics natural rhythm)
Micronized DHEA capsules
1-2g dried leaf as tea, 2-3 times daily
Between meals as tea, Divided throughout the day
Dried leaf tea
4-8 weeks
8-12 weeks
2-3 cycles
Dehydroepiandrosterone for depressive symptoms: A systematic review and meta-analysis of randomized controlled trials
Journal of neuroscience research (2020) · Meta analysis · n=742
No hormonal changes that indicated any risk to the participants' health were seen.
Hormonal Treatments and Vaginal Moisturizers for Genitourinary Syndrome of Menopause : A Systematic Review
Annals of internal medicine (2024) · Systematic review
Systematic review of 46 RCTs of at least 8 weeks in postmenopausal women with genitourinary syndrome of menopause, too varied to pool.
TEAS, DHEA, CoQ10, and GH for poor ovarian response undergoing IVF-ET: a systematic review and network meta-analysis
Reproductive biology and endocrinology : RB&E (2023) · Meta analysis · n=2323
Compared with the control group, CoQ10 (OR 2.22, 95% CI: 1.05 to 4.71) and DHEA (OR 1.92, 95% CI: 1.16 to 3.16) had obvious advantages in improving the clinical pregnancy rate.
Raspberry Leaves and Extracts-Molecular Mechanism of Action and Its Effectiveness on Human Cervical Ripening and the Induction of Labor
Nutrients (2023) · Review
The majority of women apply raspberry leaves during pregnancy to induce and ease labor.
A Review on Berry Seeds-A Special Emphasis on Their Chemical Content and Health-Promoting Properties
Nutrients (2023) · Review
A different part of the plant: berry seeds, not the leaf. Raspberry leaf is dosed as 1-2g dried leaf as tea for uterine and menstrual use, and this paper reviews the chemical content of berry seeds. Read it as species-level context, not as leaf evidence.
Phenolic Composition, Mineral Content, and Beneficial Bioactivities of Leaf Extracts from Black Currant (Ribes nigrum L.), Raspberry (Rubus idaeus), and Aronia (Aronia melanocarpa)
Nutrients (2020) · Review
Narrative review of the phenolic compounds and minerals in leaves of black currant, raspberry and aronia, not raspberry alone.
Both points come from one phase II RCT in 198 adults with knee osteoarthritis (PMID 35799169), which gave 200 mg or 400 mg of leaf extract daily for 12 weeks. The primary endpoint, WOMAC pain, did not differ from placebo at either dose. Walking pain on a VAS fell more than placebo at 400 mg only, so 200 mg is plotted as no effect. Doses above 400 mg were not tested, and a single trial cannot establish an optimal dose or a safety ceiling.
AI-estimated from published studies. Interpret as directional guidance.
DHEA has a higher evidence score (5.5/10 vs 4/10) and wins in 2 of 3 categories.
For support mood, DHEA has a higher relevance score (85 vs 60).
No documented interaction was found in the data searched. This does not establish that this exact combination is safe.
The right pick depends on your goals. Answer a few quick questions for a personalised recommendation — or dig into the full evidence on each.