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Head-to-head evidence comparison — which supplement is right for you?
DHEA wins 2 of 3 categories. Both are solid choices — the best pick depends on your specific goals.
Verdict
Probably helps
4 of 8 studies with measurable effects showed benefit.
Top outcomes
Verdict
Mostly mechanism / observational
2 of 2 studies with measurable effects showed benefit.
Top outcomes
Shared outcomes (1)
Outcomes where both DHEA and Shilajit have evidence — compare verdict strength side-by-side.
25-50mg for women; 50-100mg for men (start low)
Morning (mimics natural rhythm)
Micronized DHEA capsules
300-500mg purified extract
Morning, With or without food
Purified resin or PrimaVie extract
4-8 weeks
8-12 weeks
2-4 weeks
8-12 weeks
2-4 weeks
Dehydroepiandrosterone for depressive symptoms: A systematic review and meta-analysis of randomized controlled trials
Journal of neuroscience research (2020) · Meta analysis · n=742
No hormonal changes that indicated any risk to the participants' health were seen.
Hormonal Treatments and Vaginal Moisturizers for Genitourinary Syndrome of Menopause : A Systematic Review
Annals of internal medicine (2024) · Systematic review
Vaginal estrogen, vaginal DHEA, oral ospemifene, and vaginal moisturizers may improve some GSM symptoms in the short term.
TEAS, DHEA, CoQ10, and GH for poor ovarian response undergoing IVF-ET: a systematic review and network meta-analysis
Reproductive biology and endocrinology : RB&E (2023) · Meta analysis · n=2323
Compared with the control group, CoQ10 (OR 2.22, 95% CI: 1.05 to 4.71) and DHEA (OR 1.92, 95% CI: 1.16 to 3.16) had obvious advantages in improving the clinical pregnancy rate.
Safety and efficacy of shilajit (mumie, moomiyo)
Phytotherapy research : PTR (2014) · Systematic review
Furthermore, animal and human data support its use as a 'revitalizer', enhancing physical performance and relieving fatigue with enhanced production of ATP.
Shilajit: a review
Phytotherapy research : PTR (2007) · Systematic review
It has been found to consist of a complex mixture of organic humic substances and plant and microbial metabolites occurring in the rock rhizospheres of its natural habitat.
Effects of 12 Weeks of Chromium, Phyllanthus emblica Fruit Extract, and Shilajit Supplementation on Markers of Cardiometabolic Health, Fitness, and Weight Loss in Men and Women with Risk Factors to Metabolic Syndrome Initiating an Exercise and Diet Intervention: A Randomized Double-Blind, Placebo-Controlled Trial
Nutrients (2025) · Rct · n=166
Methods: In total, 166 sedentary men and women with at least two markers of metabolic syndrome participated in a randomized, placebo-controlled, parallel-arm, and repeated-measure intervention study, of which 109 completed the study (48.6 ± 10 yrs., 34.2 ± 6 kg/m2, 41.3 ± 7% fat).
Based on meta-analysis showing OR 1.92 for clinical pregnancy rate in poor ovarian response patients. Effect specific to fertility treatment context with medical supervision. Limited long-term safety data.
Based on 20% testosterone increase in healthy volunteers at 500mg for 90 days. Conservative estimate given systematic review found most testosterone boosters fail to increase levels. Limited to purified extracts only.
AI-estimated from published studies. Interpret as directional guidance.
DHEA has a higher evidence score (9/10 vs 8/10) and wins in 2 of 3 categories.
For menopause support, Shilajit has a higher relevance score (85 vs 78).
No known interactions between DHEA and Shilajit have been documented in our database. However, always consult a healthcare provider before combining supplements.