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Pygeum africanum (African Cherry)
African cherry bark extract that improves urinary flow and reduces nighttime urination in men with BPH — used clinically since the 1960s.
What the evidence says
Pygeum appears to help in 3 of 3 studies with measurable effects — the evidence leans clearly favourable.
Most evidence is from high-quality meta-analyses and randomised trials published 1998–2025 with a typical study size of 1,562 participants.
Based on 23 studies · 3 meta-analyses · 1 RCT · 11,162 total participants
Confidence
HighWhat the studies found
By outcome
See full supplement plans that include Pygeum.
Pygeum has an evidence score of 7/10 — strong evidence based on 23 indexed studies, including 2 meta-analyses. African cherry bark extract that improves urinary flow and reduces nighttime urination in men with BPH — used clinically since the 1960s.
The commonly studied dose of Pygeum is 100-200mg standardized extract daily. Research points to an estimated optimal dose around 150mg, with a minimum effective dose near 100mg. Individual response varies — start low and adjust.
Timing is flexible for Pygeum — consistent daily use matters more than the time of day. Pygeum africanum bark extract contains phytosterols (beta-sitosterol), pentacyclic triterpenes, and ferulic acid esters that support prostate health.
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Last reviewed May 2026 · evidence from 25 studies · how we score
This information is for educational purposes only. It is not a substitute for professional medical advice. Always consult a qualified healthcare provider before starting, stopping, or changing any supplement or medication.
Pygeum is extracted from the bark of the African cherry tree and has been used in European medicine for prostate health since the 1960s. It's one of the most well-researched natural prostate supplements, with multiple clinical trials showing benefits for benign prostatic hyperplasia (BPH) symptoms including improved urinary flow and reduced nighttime urination.
Reduces prostate inflammation
May mildly reduce DHT production
Improves bladder contractility
How Pygeum works — from molecular targets to health outcomes. Click an edge to see supporting research.This visualization is in beta — pathways are being refined and expanded.
100-200mg standardized extract daily
Loading: Not required
Can be taken without food
| Form | Type |
|---|---|
| 💊Standardized extract (13-14% sterols) | Recommended |
| 💊Capsules | Alternative |
| 💊Combination prostate formulas | Alternative |
Look for extracts standardized to 13-14% sterols. Most research uses this standardization.
Minimum: 6 weeks
Optimal: 12 weeks
Cycling: Not required
Note: Can be taken any time of day. Often combined with saw palmetto for enhanced effects.
Based on Cochrane review (n=1562) and network meta-analysis showing modest benefits. Evidence quality noted as low-to-moderate due to dated methodology in available RCTs. Most studies used standardized bark extract.
Better urine stream and reduced hesitancy
Fewer bathroom trips at night
Reduced BPH-related discomfort
Primary target population; consult doctor for proper prostate evaluation
Additive effects on prostate; may enhance benefits but monitor
May have additive effects on urinary symptoms
Tip: Take with food
Tip: Reduce dose; take with food
Both support prostate health through different mechanisms
Enhanced prostate and urinary support
Another prostate-supportive herb
Multi-herb prostate protocol
Pygeum and PSO both support prostate health through different mechanisms — bark triterpenes vs seed phytosterols
Complementary prostate support with potentially additive BPH symptom relief
Pygeum is generally well-tolerated and considered safe for most healthy adults at recommended doses. The most commonly reported side effects are GI upset, nausea. Use caution if any of these apply to you: Hormone-sensitive conditions (theoretical).
Pine Bark Extract
Likely helpsProanthocyanidin-rich extract that improves blood flow, skin elasticity, and cognitive function — backed by 160+ published studies.
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