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Head-to-head evidence comparison — which supplement is right for you?
DHM wins 2 of 3 categories. Both are solid choices — the best pick depends on your specific goals.
Verdict
Mixed evidence
1 of 3 studies with measurable effects showed benefit.
Top outcomes
Verdict
Probably helps
10 of 15 studies with measurable effects showed benefit.
Top outcomes
Shared outcomes (1)
Outcomes where both DHM and Potassium have evidence — compare verdict strength side-by-side.
300-600mg before or after drinking; 300mg daily for liver support
Before drinking alcohol, Before bed after drinking, Daily for liver support
Dihydromyricetin capsules or tablets
99-500mg daily from supplements (food provides more)
With food to reduce GI upset, Spread throughout day, During/after exercise for athletes
Potassium Citrate or Potassium Gluconate
Weeks (ongoing)
Acute
Next day
2-4 weeks
1-2 weeks
Long-term
With excess or kidney issues
Polyphenols as potential metabolism mechanisms regulators in liver protection and liver cancer prevention
Cell proliferation (2023) · Systematic review
This review systematically illustrates that various polyphenols, including resveratrol, chlorogenic acid, caffeic acid, dihydromyricetin, quercetin, catechins, curcumin, etc., improve metabolic disorders through direct or indirect pathways to protect the liver and fight liver cancer.
Flavonoids-mediated SIRT1 signaling activation in hepatic disorders
Life sciences (2020) · Systematic review
Additionally, molecular modeling simulations were applied to explore the potential binding mode of these flavonoids to SIRT1.
Metabolic mechanisms of Dihydromyricetin and strategies for enhancing its bioavailability: A recent review
Food chemistry (2025) · Systematic review
It examines the key factors influencing its bioavailability and highlights the design and construction of various bio-based delivery systems aimed at improving its bioavailability.
Effect of changes in potassium intake on blood pressure: a dose–response meta-analysis of randomized clinical trials (2000–2024)
Clinical Kidney Journal (2025) · Meta analysis · n=2500
Dose-response analysis of RCTs from 2000-2024
Magnesium and Potassium Supplementation for Systolic Blood Pressure Reduction in the General Normotensive Population: A Systematic Review and Subgroup Meta-Analysis for Optimal Dosage and Treatment Length
Nutrients (2024) · Meta analysis
Both supplements demonstrated greater reductions in SBP for the general population at lower dosages and longer treatment durations.
Sex-specific associations between sodium and potassium intake and overall and cause-specific mortality: a large prospective U.S. cohort study, systematic review, and updated meta-analysis of cohort studies
BMC medicine (2024) · Meta analysis · n=237036
Meta-analysis examining Potassium efficacy
Evidence primarily from systematic reviews examining polyphenol hepatoprotective mechanisms rather than direct DHM clinical trials. Bioavailability limitations may reduce actual effectiveness. Conservative estimates given lack of specific dose-response studies.
AI-estimated from published studies. Interpret as directional guidance.
DHM has a higher evidence score (4/10 vs 8.5/10) and wins in 2 of 3 categories.
For reduce inflammation, Potassium has a higher relevance score (85 vs 75).
No known interactions between DHM and Potassium have been documented in our database. However, always consult a healthcare provider before combining supplements.