Loading…
We use essential cookies (authentication, your saved goals/stack) by default. With your permission we’ll also enable privacy-respecting analytics (Vercel Web Analytics, anonymous load-time metrics) and error-replay diagnostics (Sentry — DOM snapshots only when an error fires) so we can fix bugs faster. Learn more about cookies
Head-to-head evidence comparison — which supplement is right for you?
Potassium vs Rutin: Potassium has the stronger overall evidence (8.5 vs 5/10); the best pick depends on your goals. Take the 60-second quiz for a pick tailored to your goals.
Potassium wins 2 of 3 categories. Both are solid choices — the best pick depends on your specific goals.
Verdict
Probably helps
2 of 3 studies with measurable effects showed benefit.
Top outcomes
Verdict
Too few graded studies
Top outcomes
Supplements commonly provide 99 mg per serving, and food provides more (no cited trial states the dose it used). No upper limit is established, so no maximum is stored. That is not a statement that larger amounts are safe.
With food to reduce GI upset, Spread throughout day, During/after exercise for athletes
Potassium Citrate or Potassium Gluconate
Oxerutins (Venoruton) ~1000mg daily; plain rutin products vary widely (a typical label dose, not the dose used in the cited trials, which used 2 g of oxerutins a day)
With meals
Hydroxyethylrutosides / oxerutins (Venoruton)
and 10 more not shown
2-4 weeks
1-2 weeks
Long-term
With excess or kidney issues
4-12 weeks
4-12 weeks
Effect of changes in potassium intake on blood pressure: a dose–response meta-analysis of randomized clinical trials (2000–2024)
Clinical Kidney Journal (2025) · Meta analysis
Our meta-analysis included 10 RCTs, comprising 4 studies on subjects without hypertension and 6 studies on subjects with hypertension.
Magnesium and Potassium Supplementation for Systolic Blood Pressure Reduction in the General Normotensive Population: A Systematic Review and Subgroup Meta-Analysis for Optimal Dosage and Treatment Length
Nutrients (2024) · Meta analysis
Both supplements demonstrated greater reductions in SBP for the general population at lower dosages and longer treatment durations.
Sex-specific associations between sodium and potassium intake and overall and cause-specific mortality: a large prospective U.S. cohort study, systematic review, and updated meta-analysis of cohort studies
BMC medicine (2024) · Meta analysis · n=416104
Prospective analysis of 237,036 men and 179,068 women in the NIH-AARP Diet and Health Study, plus an updated meta-analysis of cohort studies.
A systematic review of the efficacy and tolerability of hydroxyethylrutosides for improvement of the signs and symptoms of chronic venous insufficiency.
J Clin Pharm Ther (2015) · Meta analysis
Hydroxyethylrutosides produced MODEST improvement in CVI symptoms
Venoruton vs Daflon: evaluation of effects on quality of life in chronic venous insufficiency.
Angiology (2006) · Rct · n=90
Oxerutins (Venoruton) improved CVI quality of life
Veno-active drugs for chronic venous disease: A randomized, double-blind, placebo-controlled parallel-design trial.
Phlebology (2014) · Rct · n=136
Multi-arm comparative RCT of venoactive drugs for chronic venous disease
Potassium has a higher evidence score (8.5/10 vs 5/10) and wins in 2 of 3 categories.
No documented interaction was found in the data searched. This does not establish that this exact combination is safe.
The right pick depends on your goals. Answer a few quick questions for a personalised recommendation — or dig into the full evidence on each.