Dave Asprey — Bulletproof biohacker stack

The Bulletproof founder’s reported regimen — he claims 100+ pills/day and withholds the full list. SEVERE COI: he sells branded versions of most items (Suppgrade Labs, Bulletproof, Danger Coffee, Upgrade Labs). Documented by underlying compound, not endorsed; notable for what he has publicly stopped.

Dave Asprey is an American entrepreneur, author and advocate of a low-carbohydrate, high-fat diet known as the Bulletproof diet, about which he has made claims criticized by dietitians as pseudoscientific . He founded Bulletproof 360, Inc.

Website ↗Wikipedia ↗

Photo: Valder Beebe Show / CC BY 3.0, via Wikimedia Commons

Documented, not endorsed. What Dave Asprey reports taking (as of 2026-06) — not medical advice, not a recommendation. We sell nothing; each item links to its independently evidence-graded card.

At a glance

Aimed at (inferred from 16 mapped members)

💪 Performance & recovery 8🧬 Longevity & healthspan 8😌 Mood & stress 7🩺 General health 3🌙 Sleep 2🧠 Cognition 2

Evidence makeup

5 Strong 7 Moderate 4 Emerging

The stack · 16 compounds

Core

✨ Magnesium
His strongest first-person item — energy AM, sleep PM.
Strong 8.5500–1000 mg, split AM/PM
☀️ Vitamin D3
Hormone substrate.
Moderate 7.5~5000 IU (titrates to blood level)
🦴 Vitamin K2
Directs calcium to bone.
Moderate 6.0with D3
🐟 Omega-3
Brain/heart; prefers krill for lower contaminants.
Strong 9.01–2 g krill (switched from fish oil)
⚡ Creatine
Energy + cognition.
Strong 9.53–5 g, in coffee
🍵 L-Theanine
Caffeine synergy / calm focus.
Moderate 6.0200 mg, with coffee
✨ Collagen
Skin/gut/glycine.
Moderate 6.010+ g

Situational

⚫ Activated Charcoal
Binds mycotoxins — travel/unknown food.
Emerging 4.01000 mg
🛡️ Glutathione
Antioxidant / detox.
Emerging 4.8500–1000 mg (liposomal)
⚡ CoQ10
Mitochondrial.
Strong 8.0≥100 mg
🍇 Urolithin A
Mitophagy.
Moderate 6.0no dose info
🔬 Nicotinamide Riboside
NAD+ precursor.
Moderate 5.5no dose info (NR + NMN)
🍊 Vitamin C
Antioxidant (he is oxalate-cautious on high doses).
Strong 8.0~250 mg
🧬 Methylfolate
Methylation (discloses an MTHFR variant).
Moderate 6.0no dose info
✨ Aniracetam
Nootropic (memory/speed).
Emerging 4.0800 mg, most mornings
⚡ Phenylpiracetam
Intense focus.
Emerging 4.0100 mg, most mornings

“no dose info” = publicly known to take it, but no reliable dose has been stated.

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“Start” adds the 16 evidence-graded compounds to your own stack to edit — gated research compounds excluded. Not an endorsement.

Synergies (3)

Vitamin D3 + Magnesium — Magnesium deficiency impairs vitamin D metabolism and effectiveness
Vitamin D3 + Vitamin K2 — K2 prevents arterial calcification while enhancing bone mineralization from vitamin D
CoQ10 + Omega-3 — Taking CoQ10 with fats increases absorption by 3-5x

Documented supplement–supplement interactions between members of this stack — not a personal interaction check. Full interaction checker →

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Sources: daveasprey.com & interviews