Bryan Johnson vs David Sinclair, PhD
What they share, where they diverge, and how the evidence compares — documented, not endorsed.
Bryan Johnson
19 compounds · longevity
David Sinclair, PhD
11 compounds · longevity
Bryan Johnson
4 Strong9 Moderate4 Emerging2 Gated
🧬 Longevity & healthspan💪 Performance & recovery🧠 Cognition😌 Mood & stress
David Sinclair, PhD
6 Moderate3 Emerging2 Gated
🧬 Longevity & healthspan🫀 Cardiovascular
Shared — both take (3)
3 of 27 distinct compounds overlap (11%).
- ⏳ NMNModerate 5.5
- ☀️ Vitamin D3Moderate 7.5
- 🧀 SpermidineEmerging 4.2
Only Bryan Johnson (16)
- 🔬 Nicotinamide RibosideModerate 5.5
- 🧬 Metformingated
- ⚗️ Lithium OrotateEmerging 2.2
- ⚡ CoQ10Strong 8.0
- 🐟 Omega-3Strong 9.0
- ⚡ CreatineStrong 9.5
- ⚗️ Calcium AKGEmerging 3.5
- 💫 TaurineModerate 7.5
- 🦵 GlucosamineModerate 5.5
- 🍅 LycopeneEmerging 4.5
- 🦐 AstaxanthinModerate 5.0
- 💧 Hyaluronic AcidModerate 5.5
- 🛡️ ZincStrong 8.5
- 🌿 AshwagandhaModerate 7.5
- ✨ CollagenModerate 6.0
- 🧪 NDGA (Nordihydroguaiaretic acid)gated
Only David Sinclair, PhD (8)
- 🍷 ResveratrolEmerging 4.5
- 🌿 BerberineModerate 7.5
- 🦴 Vitamin K2Moderate 6.0
- 🩸 Rosuvastatin (Crestor)gated
- 🍓 FisetinEmerging 3.5
- 💪 TMGModerate 5.8
- ⚡ Alpha Lipoic AcidModerate 7.0
- 💊 Aspirin (low-dose)gated